Recombinant multi-species ALKBH1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ALKBH1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 2700073G19Rik,ABH,ABH1,ALKBH,ALKBH1,Abh,Alkbh,Alkbh1,Alkylated DNA repair protein alkB homolog 1,Alpha-ketoglutarate-dependent dioxygenase ABH1,DNA 6mA demethylase,DNA N6-methyl adenine demethylase ALKBH1,DNA lyase ABH1,DNA oxidative demethylase ALKBH1,Nucleic acid dioxygenase ALKBH1,alkB,hABH,mRNA N(3)-methylcytidine demethylase
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1438-Ag-1/ GM-Tg-hg-SE1438-Ag-2 | Human ALKBH1 protein | Human |
| GM-Tg-rg-SE1438-Ag-1/ GM-Tg-rg-SE1438-Ag-2 | Rat ALKBH1 protein | Rat |
| GM-Tg-mg-SE1438-Ag-1/ GM-Tg-mg-SE1438-Ag-2 | Mouse ALKBH1 protein | Mouse |
| GM-Tg-cynog-SE1438-Ag-1/ GM-Tg-cynog-SE1438-Ag-2 | Cynomolgus/Rhesus macaque ALKBH1 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1438-Ag-1/ GM-Tg-felg-SE1438-Ag-2 | Feline ALKBH1 protein | Feline |
| GM-Tg-cang-SE1438-Ag-1/ GM-Tg-cang-SE1438-Ag-2 | Canine ALKBH1 protein | Canine |
| GM-Tg-bovg-SE1438-Ag-1/ GM-Tg-bovg-SE1438-Ag-2 | Bovine ALKBH1 protein | Bovine |
| GM-Tg-equg-SE1438-Ag-1/ GM-Tg-equg-SE1438-Ag-2 | Equine ALKBH1 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-SE1438-Ag-1/ GM-Tg-hg-SE1438-Ag-2;
GM-Tg-rg-SE1438-Ag-1/ GM-Tg-rg-SE1438-Ag-2;
GM-Tg-mg-SE1438-Ag-1/ GM-Tg-mg-SE1438-Ag-2; GM-Tg-cynog-SE1438-Ag-1/ GM-Tg-cynog-SE1438-Ag-2; GM-Tg-felg-SE1438-Ag-1/ GM-Tg-felg-SE1438-Ag-2; GM-Tg-cang-SE1438-Ag-1/ GM-Tg-cang-SE1438-Ag-2; GM-Tg-bovg-SE1438-Ag-1/ GM-Tg-bovg-SE1438-Ag-2; GM-Tg-equg-SE1438-Ag-1/ GM-Tg-equg-SE1438-Ag-2 |
| Products Name | ALKBH1 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | ALKBH1 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ALKBH1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.