Recombinant multi-species DDX17 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DDX17 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and splicesosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an ATPase activated by a variety of RNA species, but not by dsDNA. This protein, and that encoded by DDX5 gene, are more closely related to each other than to any other member of the DEAD box family. This gene can encode multiple isoforms due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) start codon. [provided by RefSeq, Apr 2011]
The Alternative Names of target: 2610007K22Rik,A430025E01Rik,DDX17,DEAD box protein 17,DEAD box protein p72,DEAD box protein p82,Ddx17,Gm926,P72,Probable ATP-dependent RNA helicase DDX17,RH70,RNA-dependent helicase p72,p72
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1435-Ag-1/ GM-Tg-hg-SE1435-Ag-2 | Human DDX17 protein | Human |
| GM-Tg-rg-SE1435-Ag-1/ GM-Tg-rg-SE1435-Ag-2 | Rat DDX17 protein | Rat |
| GM-Tg-mg-SE1435-Ag-1/ GM-Tg-mg-SE1435-Ag-2 | Mouse DDX17 protein | Mouse |
| GM-Tg-cynog-SE1435-Ag-1/ GM-Tg-cynog-SE1435-Ag-2 | Cynomolgus/Rhesus macaque DDX17 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1435-Ag-1/ GM-Tg-felg-SE1435-Ag-2 | Feline DDX17 protein | Feline |
| GM-Tg-cang-SE1435-Ag-1/ GM-Tg-cang-SE1435-Ag-2 | Canine DDX17 protein | Canine |
| GM-Tg-bovg-SE1435-Ag-1/ GM-Tg-bovg-SE1435-Ag-2 | Bovine DDX17 protein | Bovine |
| GM-Tg-equg-SE1435-Ag-1/ GM-Tg-equg-SE1435-Ag-2 | Equine DDX17 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-SE1435-Ag-1/ GM-Tg-hg-SE1435-Ag-2;
GM-Tg-rg-SE1435-Ag-1/ GM-Tg-rg-SE1435-Ag-2;
GM-Tg-mg-SE1435-Ag-1/ GM-Tg-mg-SE1435-Ag-2; GM-Tg-cynog-SE1435-Ag-1/ GM-Tg-cynog-SE1435-Ag-2; GM-Tg-felg-SE1435-Ag-1/ GM-Tg-felg-SE1435-Ag-2; GM-Tg-cang-SE1435-Ag-1/ GM-Tg-cang-SE1435-Ag-2; GM-Tg-bovg-SE1435-Ag-1/ GM-Tg-bovg-SE1435-Ag-2; GM-Tg-equg-SE1435-Ag-1/ GM-Tg-equg-SE1435-Ag-2 |
| Products Name | DDX17 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | DDX17 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DDX17 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
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(PK/PD) modeling, and intricate mechanism of
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