Recombinant multi-species PAX2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PAX2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor suppressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2014]
The Alternative Names of target: FSGS7,Opdc,PAPRS,PAX-2,PAX2,Paired box protein Pax-2,Pax-2,Pax2

Target products collectionGo to PAX2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE1419-Ag-1/ GM-Tg-hg-SE1419-Ag-2 Human PAX2 protein Human
GM-Tg-rg-SE1419-Ag-1/ GM-Tg-rg-SE1419-Ag-2 Rat PAX2 protein Rat
GM-Tg-mg-SE1419-Ag-1/ GM-Tg-mg-SE1419-Ag-2 Mouse PAX2 protein Mouse
GM-Tg-cynog-SE1419-Ag-1/ GM-Tg-cynog-SE1419-Ag-2 Cynomolgus/Rhesus macaque PAX2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE1419-Ag-1/ GM-Tg-felg-SE1419-Ag-2 Feline PAX2 protein Feline
GM-Tg-cang-SE1419-Ag-1/ GM-Tg-cang-SE1419-Ag-2 Canine PAX2 protein Canine
GM-Tg-bovg-SE1419-Ag-1/ GM-Tg-bovg-SE1419-Ag-2 Bovine PAX2 protein Bovine
GM-Tg-equg-SE1419-Ag-1/ GM-Tg-equg-SE1419-Ag-2 Equine PAX2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE1419-Ag-1/ GM-Tg-hg-SE1419-Ag-2; GM-Tg-rg-SE1419-Ag-1/ GM-Tg-rg-SE1419-Ag-2;
GM-Tg-mg-SE1419-Ag-1/ GM-Tg-mg-SE1419-Ag-2; GM-Tg-cynog-SE1419-Ag-1/ GM-Tg-cynog-SE1419-Ag-2;
GM-Tg-felg-SE1419-Ag-1/ GM-Tg-felg-SE1419-Ag-2; GM-Tg-cang-SE1419-Ag-1/ GM-Tg-cang-SE1419-Ag-2;
GM-Tg-bovg-SE1419-Ag-1/ GM-Tg-bovg-SE1419-Ag-2; GM-Tg-equg-SE1419-Ag-1/ GM-Tg-equg-SE1419-Ag-2
Products Name PAX2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PAX2
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PAX2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.