Recombinant multi-species DHX8 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DHX8 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is a member of the DEAH box polypeptide family. The encoded protein contains the DEAH (Asp-Glu-Ala-His) motif which is characteristic of all DEAH box proteins, and is thought to function as an ATP-dependent RNA helicase that regulates the release of spliced mRNAs from spliceosomes prior to their export from the nucleus. This protein may be required for the replication of human immunodeficiency virus type 1 (HIV-1). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
The Alternative Names of target: ATP-dependent RNA helicase DHX8,DDX8,DEAH box protein 8,DHX8,Ddx8,Dhr2,Dhx8,HRH1,LRRGT00035,PRP22,PRPF22,RNA helicase HRH1,mDEAH6,mKIAA4096
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1414-Ag-1/ GM-Tg-hg-SE1414-Ag-2 | Human DHX8 protein | Human |
| GM-Tg-rg-SE1414-Ag-1/ GM-Tg-rg-SE1414-Ag-2 | Rat DHX8 protein | Rat |
| GM-Tg-mg-SE1414-Ag-1/ GM-Tg-mg-SE1414-Ag-2 | Mouse DHX8 protein | Mouse |
| GM-Tg-cynog-SE1414-Ag-1/ GM-Tg-cynog-SE1414-Ag-2 | Cynomolgus/Rhesus macaque DHX8 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1414-Ag-1/ GM-Tg-felg-SE1414-Ag-2 | Feline DHX8 protein | Feline |
| GM-Tg-cang-SE1414-Ag-1/ GM-Tg-cang-SE1414-Ag-2 | Canine DHX8 protein | Canine |
| GM-Tg-bovg-SE1414-Ag-1/ GM-Tg-bovg-SE1414-Ag-2 | Bovine DHX8 protein | Bovine |
| GM-Tg-equg-SE1414-Ag-1/ GM-Tg-equg-SE1414-Ag-2 | Equine DHX8 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-SE1414-Ag-1/ GM-Tg-hg-SE1414-Ag-2;
GM-Tg-rg-SE1414-Ag-1/ GM-Tg-rg-SE1414-Ag-2;
GM-Tg-mg-SE1414-Ag-1/ GM-Tg-mg-SE1414-Ag-2; GM-Tg-cynog-SE1414-Ag-1/ GM-Tg-cynog-SE1414-Ag-2; GM-Tg-felg-SE1414-Ag-1/ GM-Tg-felg-SE1414-Ag-2; GM-Tg-cang-SE1414-Ag-1/ GM-Tg-cang-SE1414-Ag-2; GM-Tg-bovg-SE1414-Ag-1/ GM-Tg-bovg-SE1414-Ag-2; GM-Tg-equg-SE1414-Ag-1/ GM-Tg-equg-SE1414-Ag-2 |
| Products Name | DHX8 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | DHX8 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DHX8 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.