Recombinant multi-species WNT8B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine WNT8B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 95%, 86% and 71% amino acid identity to the mouse, zebrafish and Xenopus Wnt8B proteins, respectively. The expression patterns of the human and mouse genes appear identical and are restricted to the developing brain. The chromosomal location of this gene to 10q24 suggests it as a candidate gene for partial epilepsy.
The Alternative Names of target: Protein Wnt-8b,WNT8B,Wnt8b

Target products collectionGo to WNT8B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE1385-Ag-1/ GM-Tg-hg-SE1385-Ag-2 Human WNT8B protein Human
GM-Tg-rg-SE1385-Ag-1/ GM-Tg-rg-SE1385-Ag-2 Rat WNT8B protein Rat
GM-Tg-mg-SE1385-Ag-1/ GM-Tg-mg-SE1385-Ag-2 Mouse WNT8B protein Mouse
GM-Tg-cynog-SE1385-Ag-1/ GM-Tg-cynog-SE1385-Ag-2 Cynomolgus/Rhesus macaque WNT8B protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE1385-Ag-1/ GM-Tg-felg-SE1385-Ag-2 Feline WNT8B protein Feline
GM-Tg-cang-SE1385-Ag-1/ GM-Tg-cang-SE1385-Ag-2 Canine WNT8B protein Canine
GM-Tg-bovg-SE1385-Ag-1/ GM-Tg-bovg-SE1385-Ag-2 Bovine WNT8B protein Bovine
GM-Tg-equg-SE1385-Ag-1/ GM-Tg-equg-SE1385-Ag-2 Equine WNT8B protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE1385-Ag-1/ GM-Tg-hg-SE1385-Ag-2; GM-Tg-rg-SE1385-Ag-1/ GM-Tg-rg-SE1385-Ag-2;
GM-Tg-mg-SE1385-Ag-1/ GM-Tg-mg-SE1385-Ag-2; GM-Tg-cynog-SE1385-Ag-1/ GM-Tg-cynog-SE1385-Ag-2;
GM-Tg-felg-SE1385-Ag-1/ GM-Tg-felg-SE1385-Ag-2; GM-Tg-cang-SE1385-Ag-1/ GM-Tg-cang-SE1385-Ag-2;
GM-Tg-bovg-SE1385-Ag-1/ GM-Tg-bovg-SE1385-Ag-2; GM-Tg-equg-SE1385-Ag-1/ GM-Tg-equg-SE1385-Ag-2
Products Name WNT8B protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name WNT8B
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine WNT8B protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.