Recombinant multi-species Trefoil factor 3/TFF3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Trefoil factor 3/TFF3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. This gene is expressed in goblet cells of the intestines and colon. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008]
The Alternative Names of target: ITF,Intestinal trefoil factor (hITF),P1B,Polypeptide P1.B (hP1.B),TFF3,TFI,Tff3,Trefoil factor 3,mITF
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1334-Ag-1/ GM-Tg-hg-SE1334-Ag-2 | Human Trefoil factor 3/TFF3 protein | Human |
| GM-Tg-rg-SE1334-Ag-1/ GM-Tg-rg-SE1334-Ag-2 | Rat Trefoil factor 3/TFF3 protein | Rat |
| GM-Tg-mg-SE1334-Ag-1/ GM-Tg-mg-SE1334-Ag-2 | Mouse Trefoil factor 3/TFF3 protein | Mouse |
| GM-Tg-cynog-SE1334-Ag-1/ GM-Tg-cynog-SE1334-Ag-2 | Cynomolgus/Rhesus macaque Trefoil factor 3/TFF3 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1334-Ag-1/ GM-Tg-felg-SE1334-Ag-2 | Feline Trefoil factor 3/TFF3 protein | Feline |
| GM-Tg-cang-SE1334-Ag-1/ GM-Tg-cang-SE1334-Ag-2 | Canine Trefoil factor 3/TFF3 protein | Canine |
| GM-Tg-bovg-SE1334-Ag-1/ GM-Tg-bovg-SE1334-Ag-2 | Bovine Trefoil factor 3/TFF3 protein | Bovine |
| GM-Tg-equg-SE1334-Ag-1/ GM-Tg-equg-SE1334-Ag-2 | Equine Trefoil factor 3/TFF3 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-SE1334-Ag-1/ GM-Tg-hg-SE1334-Ag-2;
GM-Tg-rg-SE1334-Ag-1/ GM-Tg-rg-SE1334-Ag-2;
GM-Tg-mg-SE1334-Ag-1/ GM-Tg-mg-SE1334-Ag-2; GM-Tg-cynog-SE1334-Ag-1/ GM-Tg-cynog-SE1334-Ag-2; GM-Tg-felg-SE1334-Ag-1/ GM-Tg-felg-SE1334-Ag-2; GM-Tg-cang-SE1334-Ag-1/ GM-Tg-cang-SE1334-Ag-2; GM-Tg-bovg-SE1334-Ag-1/ GM-Tg-bovg-SE1334-Ag-2; GM-Tg-equg-SE1334-Ag-1/ GM-Tg-equg-SE1334-Ag-2 |
| Products Name | Trefoil factor 3/TFF3 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | Trefoil factor 3/TFF3 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Trefoil factor 3/TFF3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.