Recombinant multi-species RETN protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RETN protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene belongs to the family defined by the mouse resistin-like genes. The characteristic feature of this family is the C-terminal stretch of 10 cys residues with identical spacing. The mouse homolog of this protein is secreted by adipocytes, and may be the hormone potentially linking obesity to type II diabetes. The encoded protein also has an antimicrobial role in skin, displaying antibacterial activity against both Gram positive and Gram negative bacteria. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2020]
The Alternative Names of target: ADSF,Adipose tissue-specific secretory factor (ADSF),C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein,Cysteine-rich secreted protein A12-alpha-like 2,Cysteine-rich secreted protein FIZZ3,FIZZ3,Fizz3,RENT,RETN,RETN1,RSTN,Resistin,Retn,Rstn,XCP1,Xcp4
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1239-Ag-1/ GM-Tg-hg-SE1239-Ag-2 | Human RETN protein | Human |
| GM-Tg-rg-SE1239-Ag-1/ GM-Tg-rg-SE1239-Ag-2 | Rat RETN protein | Rat |
| GM-Tg-mg-SE1239-Ag-1/ GM-Tg-mg-SE1239-Ag-2 | Mouse RETN protein | Mouse |
| GM-Tg-cynog-SE1239-Ag-1/ GM-Tg-cynog-SE1239-Ag-2 | Cynomolgus/Rhesus macaque RETN protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1239-Ag-1/ GM-Tg-felg-SE1239-Ag-2 | Feline RETN protein | Feline |
| GM-Tg-cang-SE1239-Ag-1/ GM-Tg-cang-SE1239-Ag-2 | Canine RETN protein | Canine |
| GM-Tg-bovg-SE1239-Ag-1/ GM-Tg-bovg-SE1239-Ag-2 | Bovine RETN protein | Bovine |
| GM-Tg-equg-SE1239-Ag-1/ GM-Tg-equg-SE1239-Ag-2 | Equine RETN protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-SE1239-Ag-1/ GM-Tg-hg-SE1239-Ag-2;
GM-Tg-rg-SE1239-Ag-1/ GM-Tg-rg-SE1239-Ag-2;
GM-Tg-mg-SE1239-Ag-1/ GM-Tg-mg-SE1239-Ag-2; GM-Tg-cynog-SE1239-Ag-1/ GM-Tg-cynog-SE1239-Ag-2; GM-Tg-felg-SE1239-Ag-1/ GM-Tg-felg-SE1239-Ag-2; GM-Tg-cang-SE1239-Ag-1/ GM-Tg-cang-SE1239-Ag-2; GM-Tg-bovg-SE1239-Ag-1/ GM-Tg-bovg-SE1239-Ag-2; GM-Tg-equg-SE1239-Ag-1/ GM-Tg-equg-SE1239-Ag-2 |
| Products Name | RETN protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | RETN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RETN protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.