Recombinant multi-species MMP19 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MMP19 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of a family of proteins that are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded protein is secreted as an inactive proprotein, which is activated upon cleavage by extracellular proteases. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Jan 2013]
The Alternative Names of target: CODA,MMP-19,MMP18,MMP19,Matrix metalloproteinase RASI,Matrix metalloproteinase-18 (MMP-18),Matrix metalloproteinase-19,Mmp19,RASI-1
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1100-Ag-1/ GM-Tg-hg-SE1100-Ag-2 | Human MMP19 protein | Human |
| GM-Tg-rg-SE1100-Ag-1/ GM-Tg-rg-SE1100-Ag-2 | Rat MMP19 protein | Rat |
| GM-Tg-mg-SE1100-Ag-1/ GM-Tg-mg-SE1100-Ag-2 | Mouse MMP19 protein | Mouse |
| GM-Tg-cynog-SE1100-Ag-1/ GM-Tg-cynog-SE1100-Ag-2 | Cynomolgus/Rhesus macaque MMP19 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1100-Ag-1/ GM-Tg-felg-SE1100-Ag-2 | Feline MMP19 protein | Feline |
| GM-Tg-cang-SE1100-Ag-1/ GM-Tg-cang-SE1100-Ag-2 | Canine MMP19 protein | Canine |
| GM-Tg-bovg-SE1100-Ag-1/ GM-Tg-bovg-SE1100-Ag-2 | Bovine MMP19 protein | Bovine |
| GM-Tg-equg-SE1100-Ag-1/ GM-Tg-equg-SE1100-Ag-2 | Equine MMP19 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-SE1100-Ag-1/ GM-Tg-hg-SE1100-Ag-2;
GM-Tg-rg-SE1100-Ag-1/ GM-Tg-rg-SE1100-Ag-2;
GM-Tg-mg-SE1100-Ag-1/ GM-Tg-mg-SE1100-Ag-2; GM-Tg-cynog-SE1100-Ag-1/ GM-Tg-cynog-SE1100-Ag-2; GM-Tg-felg-SE1100-Ag-1/ GM-Tg-felg-SE1100-Ag-2; GM-Tg-cang-SE1100-Ag-1/ GM-Tg-cang-SE1100-Ag-2; GM-Tg-bovg-SE1100-Ag-1/ GM-Tg-bovg-SE1100-Ag-2; GM-Tg-equg-SE1100-Ag-1/ GM-Tg-equg-SE1100-Ag-2 |
| Products Name | MMP19 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | MMP19 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MMP19 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.