Recombinant multi-species MASP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MASP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010]
The Alternative Names of target: 3MC1,CCPII,CRARF,CRARF1,Complement factor MASP-3,Complement-activating component of Ra-reactive factor,Crarf,MAP-1,MAP1,MASP,MASP-3,MASP1,MASP3,MAp44,Mannan-binding lectin serine protease 1,Mannose-binding lectin-associated serine protease 1 (MASP-1),Mannose-binding protein-associated serine protease,Masp1,Masp1/3,Masp3,PRSS5,RPIB9,Ra-reactive factor serine protease p100 (RaRF),RaRF,Serine protease 5

Target products collectionGo to MASP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE1089-Ag-1/ GM-Tg-hg-SE1089-Ag-2 Human MASP1 protein Human
GM-Tg-rg-SE1089-Ag-1/ GM-Tg-rg-SE1089-Ag-2 Rat MASP1 protein Rat
GM-Tg-mg-SE1089-Ag-1/ GM-Tg-mg-SE1089-Ag-2 Mouse MASP1 protein Mouse
GM-Tg-cynog-SE1089-Ag-1/ GM-Tg-cynog-SE1089-Ag-2 Cynomolgus/Rhesus macaque MASP1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE1089-Ag-1/ GM-Tg-felg-SE1089-Ag-2 Feline MASP1 protein Feline
GM-Tg-cang-SE1089-Ag-1/ GM-Tg-cang-SE1089-Ag-2 Canine MASP1 protein Canine
GM-Tg-bovg-SE1089-Ag-1/ GM-Tg-bovg-SE1089-Ag-2 Bovine MASP1 protein Bovine
GM-Tg-equg-SE1089-Ag-1/ GM-Tg-equg-SE1089-Ag-2 Equine MASP1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE1089-Ag-1/ GM-Tg-hg-SE1089-Ag-2; GM-Tg-rg-SE1089-Ag-1/ GM-Tg-rg-SE1089-Ag-2;
GM-Tg-mg-SE1089-Ag-1/ GM-Tg-mg-SE1089-Ag-2; GM-Tg-cynog-SE1089-Ag-1/ GM-Tg-cynog-SE1089-Ag-2;
GM-Tg-felg-SE1089-Ag-1/ GM-Tg-felg-SE1089-Ag-2; GM-Tg-cang-SE1089-Ag-1/ GM-Tg-cang-SE1089-Ag-2;
GM-Tg-bovg-SE1089-Ag-1/ GM-Tg-bovg-SE1089-Ag-2; GM-Tg-equg-SE1089-Ag-1/ GM-Tg-equg-SE1089-Ag-2
Products Name MASP1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MASP1
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MASP1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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