Recombinant multi-species KLK11/Kallikrein 11 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KLK11/Kallikrein 11 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing and the use of alternate promoters results in multiple transcript variants encoding distinct isoforms which are differentially expressed. [provided by RefSeq, Dec 2016]
The Alternative Names of target: 2310015I08Rik,Hippostasin,IEKD,KLK11,Kallikrein 11,Kallikrein-11,Klk11,Klng,PRSS20,Prss20,Serine protease 20,TLSP,Trypsin-like protease,hK11

Target products collectionGo to KLK11/Kallikrein 11 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE1048-Ag-1/ GM-Tg-hg-SE1048-Ag-2 Human KLK11/Kallikrein 11 protein Human
GM-Tg-rg-SE1048-Ag-1/ GM-Tg-rg-SE1048-Ag-2 Rat KLK11/Kallikrein 11 protein Rat
GM-Tg-mg-SE1048-Ag-1/ GM-Tg-mg-SE1048-Ag-2 Mouse KLK11/Kallikrein 11 protein Mouse
GM-Tg-cynog-SE1048-Ag-1/ GM-Tg-cynog-SE1048-Ag-2 Cynomolgus/Rhesus macaque KLK11/Kallikrein 11 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE1048-Ag-1/ GM-Tg-felg-SE1048-Ag-2 Feline KLK11/Kallikrein 11 protein Feline
GM-Tg-cang-SE1048-Ag-1/ GM-Tg-cang-SE1048-Ag-2 Canine KLK11/Kallikrein 11 protein Canine
GM-Tg-bovg-SE1048-Ag-1/ GM-Tg-bovg-SE1048-Ag-2 Bovine KLK11/Kallikrein 11 protein Bovine
GM-Tg-equg-SE1048-Ag-1/ GM-Tg-equg-SE1048-Ag-2 Equine KLK11/Kallikrein 11 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE1048-Ag-1/ GM-Tg-hg-SE1048-Ag-2; GM-Tg-rg-SE1048-Ag-1/ GM-Tg-rg-SE1048-Ag-2;
GM-Tg-mg-SE1048-Ag-1/ GM-Tg-mg-SE1048-Ag-2; GM-Tg-cynog-SE1048-Ag-1/ GM-Tg-cynog-SE1048-Ag-2;
GM-Tg-felg-SE1048-Ag-1/ GM-Tg-felg-SE1048-Ag-2; GM-Tg-cang-SE1048-Ag-1/ GM-Tg-cang-SE1048-Ag-2;
GM-Tg-bovg-SE1048-Ag-1/ GM-Tg-bovg-SE1048-Ag-2; GM-Tg-equg-SE1048-Ag-1/ GM-Tg-equg-SE1048-Ag-2
Products Name KLK11/Kallikrein 11 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name KLK11/Kallikrein 11
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KLK11/Kallikrein 11 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.