Recombinant multi-species KAZALD1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KAZALD1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a secreted member of the insulin growth factor-binding protein (IGFBP) superfamily. The protein contains an insulin growth factor-binding domain in its N-terminal region, a Kazal-type serine protease inhibitor and follistatin-like domain in its central region, and an immunoglobulin-like domain in its C-terminal region. Studies of the mouse ortholog suggest that this protein may function in bone development and bone regeneration. This gene is hypomethylated and over-expressed in high-grade glioma compared to low-grade glioma, and thus the hypomethylated gene may be associated with cell proliferation and the shorter survival of patients with high-grade glioma. It is also one of numerous genes found to be deleted in a novel 5.54 Mb interstitial deletion, which is associated with multiple congenital anomalies. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
The Alternative Names of target: BONO1,Bono1,FKSG28,FKSG40,IGFBP-rP10,KAZALD1,Kazal-type serine protease inhibitor domain-containing protein 1,Kazald1

Target products collectionGo to KAZALD1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE1044-Ag-1/ GM-Tg-hg-SE1044-Ag-2 Human KAZALD1 protein Human
GM-Tg-rg-SE1044-Ag-1/ GM-Tg-rg-SE1044-Ag-2 Rat KAZALD1 protein Rat
GM-Tg-mg-SE1044-Ag-1/ GM-Tg-mg-SE1044-Ag-2 Mouse KAZALD1 protein Mouse
GM-Tg-cynog-SE1044-Ag-1/ GM-Tg-cynog-SE1044-Ag-2 Cynomolgus/Rhesus macaque KAZALD1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE1044-Ag-1/ GM-Tg-felg-SE1044-Ag-2 Feline KAZALD1 protein Feline
GM-Tg-cang-SE1044-Ag-1/ GM-Tg-cang-SE1044-Ag-2 Canine KAZALD1 protein Canine
GM-Tg-bovg-SE1044-Ag-1/ GM-Tg-bovg-SE1044-Ag-2 Bovine KAZALD1 protein Bovine
GM-Tg-equg-SE1044-Ag-1/ GM-Tg-equg-SE1044-Ag-2 Equine KAZALD1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE1044-Ag-1/ GM-Tg-hg-SE1044-Ag-2; GM-Tg-rg-SE1044-Ag-1/ GM-Tg-rg-SE1044-Ag-2;
GM-Tg-mg-SE1044-Ag-1/ GM-Tg-mg-SE1044-Ag-2; GM-Tg-cynog-SE1044-Ag-1/ GM-Tg-cynog-SE1044-Ag-2;
GM-Tg-felg-SE1044-Ag-1/ GM-Tg-felg-SE1044-Ag-2; GM-Tg-cang-SE1044-Ag-1/ GM-Tg-cang-SE1044-Ag-2;
GM-Tg-bovg-SE1044-Ag-1/ GM-Tg-bovg-SE1044-Ag-2; GM-Tg-equg-SE1044-Ag-1/ GM-Tg-equg-SE1044-Ag-2
Products Name KAZALD1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name KAZALD1
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KAZALD1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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