Recombinant multi-species GHRH protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GHRH protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the glucagon family of proteins. The encoded preproprotein is produced in the hypothalamus and cleaved to generate the mature factor, known as somatoliberin, which acts to stimulate growth hormone release from the pituitary gland. Variant receptors for somatoliberin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this gene are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]
The Alternative Names of target: GHRF,GHRH,GRF,Ghrf,Ghrh,Growth hormone-releasing factor (GRF),Growth hormone-releasing hormone (GHRH),INN,Somatocrinin,Somatoliberin,Somatorelin

Target products collectionGo to GHRH products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0946-Ag-1/ GM-Tg-hg-SE0946-Ag-2 Human GHRH protein Human
GM-Tg-rg-SE0946-Ag-1/ GM-Tg-rg-SE0946-Ag-2 Rat GHRH protein Rat
GM-Tg-mg-SE0946-Ag-1/ GM-Tg-mg-SE0946-Ag-2 Mouse GHRH protein Mouse
GM-Tg-cynog-SE0946-Ag-1/ GM-Tg-cynog-SE0946-Ag-2 Cynomolgus/Rhesus macaque GHRH protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0946-Ag-1/ GM-Tg-felg-SE0946-Ag-2 Feline GHRH protein Feline
GM-Tg-cang-SE0946-Ag-1/ GM-Tg-cang-SE0946-Ag-2 Canine GHRH protein Canine
GM-Tg-bovg-SE0946-Ag-1/ GM-Tg-bovg-SE0946-Ag-2 Bovine GHRH protein Bovine
GM-Tg-equg-SE0946-Ag-1/ GM-Tg-equg-SE0946-Ag-2 Equine GHRH protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0946-Ag-1/ GM-Tg-hg-SE0946-Ag-2; GM-Tg-rg-SE0946-Ag-1/ GM-Tg-rg-SE0946-Ag-2;
GM-Tg-mg-SE0946-Ag-1/ GM-Tg-mg-SE0946-Ag-2; GM-Tg-cynog-SE0946-Ag-1/ GM-Tg-cynog-SE0946-Ag-2;
GM-Tg-felg-SE0946-Ag-1/ GM-Tg-felg-SE0946-Ag-2; GM-Tg-cang-SE0946-Ag-1/ GM-Tg-cang-SE0946-Ag-2;
GM-Tg-bovg-SE0946-Ag-1/ GM-Tg-bovg-SE0946-Ag-2; GM-Tg-equg-SE0946-Ag-1/ GM-Tg-equg-SE0946-Ag-2
Products Name GHRH protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name GHRH
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GHRH protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.