Recombinant multi-species ALR/GFER protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ALR/GFER protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factors responsible for the extraordinary regenerative capacity of mammalian liver. It has also been called hepatic regenerative stimulation substance (HSS). The gene resides on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1). The putative gene product is 42% similar to the scERV1 protein of yeast. The yeast scERV1 gene had been found to be essential for oxidative phosphorylation, the maintenance of mitochondrial genomes, and the cell division cycle. The human gene is both the structural and functional homolog of the yeast scERV1 gene. [provided by RefSeq, Jul 2008]
The Alternative Names of target: ALR,Alr,Augmenter of liver regeneration (hERV1),ERV1,FAD-linked sulfhydryl oxidase ALR,GFER,Gfer,HERV1,HPO,HPO1,HPO2,HSS,Hepatopoietin,MMCHD,MPMCD
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0943-Ag-1/ GM-Tg-hg-SE0943-Ag-2 | Human ALR/GFER protein | Human |
| GM-Tg-rg-SE0943-Ag-1/ GM-Tg-rg-SE0943-Ag-2 | Rat ALR/GFER protein | Rat |
| GM-Tg-mg-SE0943-Ag-1/ GM-Tg-mg-SE0943-Ag-2 | Mouse ALR/GFER protein | Mouse |
| GM-Tg-cynog-SE0943-Ag-1/ GM-Tg-cynog-SE0943-Ag-2 | Cynomolgus/Rhesus macaque ALR/GFER protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0943-Ag-1/ GM-Tg-felg-SE0943-Ag-2 | Feline ALR/GFER protein | Feline |
| GM-Tg-cang-SE0943-Ag-1/ GM-Tg-cang-SE0943-Ag-2 | Canine ALR/GFER protein | Canine |
| GM-Tg-bovg-SE0943-Ag-1/ GM-Tg-bovg-SE0943-Ag-2 | Bovine ALR/GFER protein | Bovine |
| GM-Tg-equg-SE0943-Ag-1/ GM-Tg-equg-SE0943-Ag-2 | Equine ALR/GFER protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-SE0943-Ag-1/ GM-Tg-hg-SE0943-Ag-2;
GM-Tg-rg-SE0943-Ag-1/ GM-Tg-rg-SE0943-Ag-2;
GM-Tg-mg-SE0943-Ag-1/ GM-Tg-mg-SE0943-Ag-2; GM-Tg-cynog-SE0943-Ag-1/ GM-Tg-cynog-SE0943-Ag-2; GM-Tg-felg-SE0943-Ag-1/ GM-Tg-felg-SE0943-Ag-2; GM-Tg-cang-SE0943-Ag-1/ GM-Tg-cang-SE0943-Ag-2; GM-Tg-bovg-SE0943-Ag-1/ GM-Tg-bovg-SE0943-Ag-2; GM-Tg-equg-SE0943-Ag-1/ GM-Tg-equg-SE0943-Ag-2 |
| Products Name | ALR/GFER protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | ALR/GFER |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ALR/GFER protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
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innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.