Recombinant multi-species FGF22 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FGF22 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
The Alternative Names of target: FGF22,Fibroblast growth factor 22,FGF-22
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Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-SE0920-Ab-1/ GM-Tg-hg-SE0920-Ab-2 | Human FGF22 protein | Human |
GM-Tg-rg-SE0920-Ab-1/ GM-Tg-rg-SE0920-Ab-2 | Rat FGF22 protein | Rat |
GM-Tg-mg-SE0920-Ab-1/ GM-Tg-mg-SE0920-Ab-2 | Mouse FGF22 protein | Mouse |
GM-Tg-cynog-SE0920-Ab-1/ GM-Tg-cynog-SE0920-Ab-2 | Cynomolgus/Rhesus macaque FGF22 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-SE0920-Ab-1/ GM-Tg-felg-SE0920-Ab-2 | Feline FGF22 protein | Feline |
GM-Tg-cang-SE0920-Ab-1/ GM-Tg-cang-SE0920-Ab-2 | Canine FGF22 protein | Canine |
GM-Tg-bovg-SE0920-Ab-1/ GM-Tg-bovg-SE0920-Ab-2 | Bovine FGF22 protein | Bovine |
GM-Tg-equg-SE0920-Ab-1/ GM-Tg-equg-SE0920-Ab-2 | Equine FGF22 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. |
GM-Tg-hg-SE0920-Ab-1/ GM-Tg-hg-SE0920-Ab-2;
GM-Tg-rg-SE0920-Ab-1/ GM-Tg-rg-SE0920-Ab-2;
GM-Tg-mg-SE0920-Ab-1/ GM-Tg-mg-SE0920-Ab-2; GM-Tg-cynog-SE0920-Ab-1/ GM-Tg-cynog-SE0920-Ab-2; GM-Tg-felg-SE0920-Ab-1/ GM-Tg-felg-SE0920-Ab-2; GM-Tg-cang-SE0920-Ab-1/ GM-Tg-cang-SE0920-Ab-2; GM-Tg-bovg-SE0920-Ab-1/ GM-Tg-bovg-SE0920-Ab-2; GM-Tg-equg-SE0920-Ab-1/ GM-Tg-equg-SE0920-Ab-2 |
Products Name | FGF22 protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | FGF22 |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FGF22 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab
GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.