Recombinant multi-species Endothelin 3/EDN3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Endothelin 3/EDN3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]
The Alternative Names of target: EDN3,ET-3,ET3,Edn3,Endothelin 3,Endothelin-3,Et3,HSCR4,PPET3,Preproendothelin-3 (PPET3),RGD1564825,WS4B,ls,preproET-3,tmgc48

Target products collectionGo to Endothelin 3/EDN3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0899-Ag-1/ GM-Tg-hg-SE0899-Ag-2 Human Endothelin 3/EDN3 protein Human
GM-Tg-rg-SE0899-Ag-1/ GM-Tg-rg-SE0899-Ag-2 Rat Endothelin 3/EDN3 protein Rat
GM-Tg-mg-SE0899-Ag-1/ GM-Tg-mg-SE0899-Ag-2 Mouse Endothelin 3/EDN3 protein Mouse
GM-Tg-cynog-SE0899-Ag-1/ GM-Tg-cynog-SE0899-Ag-2 Cynomolgus/Rhesus macaque Endothelin 3/EDN3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0899-Ag-1/ GM-Tg-felg-SE0899-Ag-2 Feline Endothelin 3/EDN3 protein Feline
GM-Tg-cang-SE0899-Ag-1/ GM-Tg-cang-SE0899-Ag-2 Canine Endothelin 3/EDN3 protein Canine
GM-Tg-bovg-SE0899-Ag-1/ GM-Tg-bovg-SE0899-Ag-2 Bovine Endothelin 3/EDN3 protein Bovine
GM-Tg-equg-SE0899-Ag-1/ GM-Tg-equg-SE0899-Ag-2 Equine Endothelin 3/EDN3 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0899-Ag-1/ GM-Tg-hg-SE0899-Ag-2; GM-Tg-rg-SE0899-Ag-1/ GM-Tg-rg-SE0899-Ag-2;
GM-Tg-mg-SE0899-Ag-1/ GM-Tg-mg-SE0899-Ag-2; GM-Tg-cynog-SE0899-Ag-1/ GM-Tg-cynog-SE0899-Ag-2;
GM-Tg-felg-SE0899-Ag-1/ GM-Tg-felg-SE0899-Ag-2; GM-Tg-cang-SE0899-Ag-1/ GM-Tg-cang-SE0899-Ag-2;
GM-Tg-bovg-SE0899-Ag-1/ GM-Tg-bovg-SE0899-Ag-2; GM-Tg-equg-SE0899-Ag-1/ GM-Tg-equg-SE0899-Ag-2
Products Name Endothelin 3/EDN3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name Endothelin 3/EDN3
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Endothelin 3/EDN3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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