Recombinant multi-species CES4A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CES4A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They also participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This gene, also called CES6, encodes a secreted enzyme, and may play a role in the detoxification of drugs and xenobiotics in neural and other tissues of the body and in the cerebrospinal fluid. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature and/or biological validity of some variants have not been determined. [provided by RefSeq, Jun 2010]
The Alternative Names of target: CES4A,Carboxylesterase 4A,CES6,CES8
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Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-SE0760-Ab-1/ GM-Tg-hg-SE0760-Ab-2 | Human CES4A protein | Human |
GM-Tg-rg-SE0760-Ab-1/ GM-Tg-rg-SE0760-Ab-2 | Rat CES4A protein | Rat |
GM-Tg-mg-SE0760-Ab-1/ GM-Tg-mg-SE0760-Ab-2 | Mouse CES4A protein | Mouse |
GM-Tg-cynog-SE0760-Ab-1/ GM-Tg-cynog-SE0760-Ab-2 | Cynomolgus/Rhesus macaque CES4A monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-SE0760-Ab-1/ GM-Tg-felg-SE0760-Ab-2 | Feline CES4A protein | Feline |
GM-Tg-cang-SE0760-Ab-1/ GM-Tg-cang-SE0760-Ab-2 | Canine CES4A protein | Canine |
GM-Tg-bovg-SE0760-Ab-1/ GM-Tg-bovg-SE0760-Ab-2 | Bovine CES4A protein | Bovine |
GM-Tg-equg-SE0760-Ab-1/ GM-Tg-equg-SE0760-Ab-2 | Equine CES4A protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. |
GM-Tg-hg-SE0760-Ab-1/ GM-Tg-hg-SE0760-Ab-2;
GM-Tg-rg-SE0760-Ab-1/ GM-Tg-rg-SE0760-Ab-2;
GM-Tg-mg-SE0760-Ab-1/ GM-Tg-mg-SE0760-Ab-2; GM-Tg-cynog-SE0760-Ab-1/ GM-Tg-cynog-SE0760-Ab-2; GM-Tg-felg-SE0760-Ab-1/ GM-Tg-felg-SE0760-Ab-2; GM-Tg-cang-SE0760-Ab-1/ GM-Tg-cang-SE0760-Ab-2; GM-Tg-bovg-SE0760-Ab-1/ GM-Tg-bovg-SE0760-Ab-2; GM-Tg-equg-SE0760-Ab-1/ GM-Tg-equg-SE0760-Ab-2 |
Products Name | CES4A protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | CES4A |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CES4A protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab
GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.