Recombinant multi-species CCN5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CCN5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. The encoded protein lacks the CT domain which is implicated in dimerization and heparin binding. It is 72% identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover. [provided by RefSeq, Jul 2008]
The Alternative Names of target: CCN5,CCN family member 5,Connective tissue growth factor-like protein (CTGF-L), Connective tissue growth factor-related protein 58, WNT1-inducible-signaling pathway protein 2 (WISP-2),CT58,WISP2,CTGF-L

Target products collectionGo to CCN5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0753-Ab-1/ GM-Tg-hg-SE0753-Ab-2 Human CCN5 protein Human
GM-Tg-rg-SE0753-Ab-1/ GM-Tg-rg-SE0753-Ab-2 Rat CCN5 protein Rat
GM-Tg-mg-SE0753-Ab-1/ GM-Tg-mg-SE0753-Ab-2 Mouse CCN5 protein Mouse
GM-Tg-cynog-SE0753-Ab-1/ GM-Tg-cynog-SE0753-Ab-2 Cynomolgus/Rhesus macaque CCN5 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0753-Ab-1/ GM-Tg-felg-SE0753-Ab-2 Feline CCN5 protein Feline
GM-Tg-cang-SE0753-Ab-1/ GM-Tg-cang-SE0753-Ab-2 Canine CCN5 protein Canine
GM-Tg-bovg-SE0753-Ab-1/ GM-Tg-bovg-SE0753-Ab-2 Bovine CCN5 protein Bovine
GM-Tg-equg-SE0753-Ab-1/ GM-Tg-equg-SE0753-Ab-2 Equine CCN5 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0753-Ab-1/ GM-Tg-hg-SE0753-Ab-2; GM-Tg-rg-SE0753-Ab-1/ GM-Tg-rg-SE0753-Ab-2;
GM-Tg-mg-SE0753-Ab-1/ GM-Tg-mg-SE0753-Ab-2; GM-Tg-cynog-SE0753-Ab-1/ GM-Tg-cynog-SE0753-Ab-2;
GM-Tg-felg-SE0753-Ab-1/ GM-Tg-felg-SE0753-Ab-2; GM-Tg-cang-SE0753-Ab-1/ GM-Tg-cang-SE0753-Ab-2;
GM-Tg-bovg-SE0753-Ab-1/ GM-Tg-bovg-SE0753-Ab-2; GM-Tg-equg-SE0753-Ab-1/ GM-Tg-equg-SE0753-Ab-2
Products Name CCN5 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CCN5
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CCN5 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.