Recombinant multi-species CCL16 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CCL16 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for lymphocytes and monocytes but not for neutrophils. This cytokine also shows a potent myelosuppressive activity and suppresses proliferation of myeloid progenitor cells. The expression of this gene is upregulated by IL-10. [provided by RefSeq, Jul 2008]
The Alternative Names of target: CCL16,C-C motif chemokine 16,Chemokine CC-4 (HCC-4), Chemokine LEC, IL-10-inducible chemokine, LCC-1, Liver-expressed chemokine, Lymphocyte and monocyte chemoattractant (LMC), Monotactin-1 (MTN-1), NCC-4, Small-inducible cytokine A16,LEC,LMC,NCC4,CKb12,HCC-4,LCC-1,Mtn-1,NCC-4,SCYL4,ILINCK,SCYA16
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Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-SE0741-Ab-1/ GM-Tg-hg-SE0741-Ab-2 | Human CCL16 protein | Human |
GM-Tg-rg-SE0741-Ab-1/ GM-Tg-rg-SE0741-Ab-2 | Rat CCL16 protein | Rat |
GM-Tg-mg-SE0741-Ab-1/ GM-Tg-mg-SE0741-Ab-2 | Mouse CCL16 protein | Mouse |
GM-Tg-cynog-SE0741-Ab-1/ GM-Tg-cynog-SE0741-Ab-2 | Cynomolgus/Rhesus macaque CCL16 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-SE0741-Ab-1/ GM-Tg-felg-SE0741-Ab-2 | Feline CCL16 protein | Feline |
GM-Tg-cang-SE0741-Ab-1/ GM-Tg-cang-SE0741-Ab-2 | Canine CCL16 protein | Canine |
GM-Tg-bovg-SE0741-Ab-1/ GM-Tg-bovg-SE0741-Ab-2 | Bovine CCL16 protein | Bovine |
GM-Tg-equg-SE0741-Ab-1/ GM-Tg-equg-SE0741-Ab-2 | Equine CCL16 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. |
GM-Tg-hg-SE0741-Ab-1/ GM-Tg-hg-SE0741-Ab-2;
GM-Tg-rg-SE0741-Ab-1/ GM-Tg-rg-SE0741-Ab-2;
GM-Tg-mg-SE0741-Ab-1/ GM-Tg-mg-SE0741-Ab-2; GM-Tg-cynog-SE0741-Ab-1/ GM-Tg-cynog-SE0741-Ab-2; GM-Tg-felg-SE0741-Ab-1/ GM-Tg-felg-SE0741-Ab-2; GM-Tg-cang-SE0741-Ab-1/ GM-Tg-cang-SE0741-Ab-2; GM-Tg-bovg-SE0741-Ab-1/ GM-Tg-bovg-SE0741-Ab-2; GM-Tg-equg-SE0741-Ab-1/ GM-Tg-equg-SE0741-Ab-2 |
Products Name | CCL16 protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | CCL16 |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CCL16 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab
GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.