Recombinant multi-species ADAMTS18 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ADAMTS18 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protein, which may regulate hemostatic balance and function as a tumor suppressor. Mutations in this gene may be associated with microcornea, myopic chorioretinal atrophy, and telecanthus (MMCAT) and cone-rod dystrophy in human patients. [provided by RefSeq, May 2016]
The Alternative Names of target: 9630038L21,A disintegrin and metalloproteinase with thrombospondin motifs 18,ADAM-TS 18,ADAM-TS18,ADAMTS-18,ADAMTS18,ADAMTS21,Adamts18,E130314N14Rik,KNO2,MMCAT,RGD1560118
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0643-Ag-1/ GM-Tg-hg-SE0643-Ag-2 | Human ADAMTS18 protein | Human |
| GM-Tg-rg-SE0643-Ag-1/ GM-Tg-rg-SE0643-Ag-2 | Rat ADAMTS18 protein | Rat |
| GM-Tg-mg-SE0643-Ag-1/ GM-Tg-mg-SE0643-Ag-2 | Mouse ADAMTS18 protein | Mouse |
| GM-Tg-cynog-SE0643-Ag-1/ GM-Tg-cynog-SE0643-Ag-2 | Cynomolgus/Rhesus macaque ADAMTS18 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0643-Ag-1/ GM-Tg-felg-SE0643-Ag-2 | Feline ADAMTS18 protein | Feline |
| GM-Tg-cang-SE0643-Ag-1/ GM-Tg-cang-SE0643-Ag-2 | Canine ADAMTS18 protein | Canine |
| GM-Tg-bovg-SE0643-Ag-1/ GM-Tg-bovg-SE0643-Ag-2 | Bovine ADAMTS18 protein | Bovine |
| GM-Tg-equg-SE0643-Ag-1/ GM-Tg-equg-SE0643-Ag-2 | Equine ADAMTS18 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-SE0643-Ag-1/ GM-Tg-hg-SE0643-Ag-2;
GM-Tg-rg-SE0643-Ag-1/ GM-Tg-rg-SE0643-Ag-2;
GM-Tg-mg-SE0643-Ag-1/ GM-Tg-mg-SE0643-Ag-2; GM-Tg-cynog-SE0643-Ag-1/ GM-Tg-cynog-SE0643-Ag-2; GM-Tg-felg-SE0643-Ag-1/ GM-Tg-felg-SE0643-Ag-2; GM-Tg-cang-SE0643-Ag-1/ GM-Tg-cang-SE0643-Ag-2; GM-Tg-bovg-SE0643-Ag-1/ GM-Tg-bovg-SE0643-Ag-2; GM-Tg-equg-SE0643-Ag-1/ GM-Tg-equg-SE0643-Ag-2 |
| Products Name | ADAMTS18 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | ADAMTS18 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ADAMTS18 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
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Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
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innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.