Recombinant multi-species ADAMTS14 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ADAMTS14 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme cleaves amino-terminal propeptides from type I procollagen, a necessary step in the formation of collagen fibers. Mutations in this gene may be associated with osteoarthritis in human patients. [provided by RefSeq, May 2016]
The Alternative Names of target: ADAMTS14,A disintegrin and metalloproteinase with thrombospondin motifs 14,ADAM-TS 14, ADAM-TS14, ADAMTS-14

Target products collectionGo to ADAMTS14 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0640-Ab-1/ GM-Tg-hg-SE0640-Ab-2 Human ADAMTS14 protein Human
GM-Tg-rg-SE0640-Ab-1/ GM-Tg-rg-SE0640-Ab-2 Rat ADAMTS14 protein Rat
GM-Tg-mg-SE0640-Ab-1/ GM-Tg-mg-SE0640-Ab-2 Mouse ADAMTS14 protein Mouse
GM-Tg-cynog-SE0640-Ab-1/ GM-Tg-cynog-SE0640-Ab-2 Cynomolgus/Rhesus macaque ADAMTS14 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0640-Ab-1/ GM-Tg-felg-SE0640-Ab-2 Feline ADAMTS14 protein Feline
GM-Tg-cang-SE0640-Ab-1/ GM-Tg-cang-SE0640-Ab-2 Canine ADAMTS14 protein Canine
GM-Tg-bovg-SE0640-Ab-1/ GM-Tg-bovg-SE0640-Ab-2 Bovine ADAMTS14 protein Bovine
GM-Tg-equg-SE0640-Ab-1/ GM-Tg-equg-SE0640-Ab-2 Equine ADAMTS14 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0640-Ab-1/ GM-Tg-hg-SE0640-Ab-2; GM-Tg-rg-SE0640-Ab-1/ GM-Tg-rg-SE0640-Ab-2;
GM-Tg-mg-SE0640-Ab-1/ GM-Tg-mg-SE0640-Ab-2; GM-Tg-cynog-SE0640-Ab-1/ GM-Tg-cynog-SE0640-Ab-2;
GM-Tg-felg-SE0640-Ab-1/ GM-Tg-felg-SE0640-Ab-2; GM-Tg-cang-SE0640-Ab-1/ GM-Tg-cang-SE0640-Ab-2;
GM-Tg-bovg-SE0640-Ab-1/ GM-Tg-bovg-SE0640-Ab-2; GM-Tg-equg-SE0640-Ab-1/ GM-Tg-equg-SE0640-Ab-2
Products Name ADAMTS14 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name ADAMTS14
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ADAMTS14 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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