Recombinant multi-species IL-36RN/IL36RN protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL-36RN/IL36RN protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine was shown to specifically inhibit the activation of NF-kappaB induced by interleukin 1 family, member 6 (IL1F6). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]
The Alternative Names of target: FIL1,FIL1 delta,FIL1(DELTA),FIL1D,Fil1delta,IL-1-related protein 3 (IL-1RP3),IL-36RN,IL-36Ra,IL1F5,IL1HY1,IL1L1,IL1RP3,IL36RA,IL36RN,If36rn,Il-1h3,Il1f5,Il1hy1,Il36rn,Interleukin-1 HY1 (IL-1HY1),Interleukin-1 delta (IL-1 delta),Interleukin-1 family member 5 (IL-1F5),Interleukin-1 receptor antagonist homolog 1 (IL-1ra homolog 1),Interleukin-1-like protein 1 (IL-1L1),Interleukin-36 receptor antagonist protein,PSORP,PSORS14

Target products collectionGo to IL-36RN/IL36RN products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0627-Ag-1/ GM-Tg-hg-SE0627-Ag-2 Human IL-36RN/IL36RN protein Human
GM-Tg-rg-SE0627-Ag-1/ GM-Tg-rg-SE0627-Ag-2 Rat IL-36RN/IL36RN protein Rat
GM-Tg-mg-SE0627-Ag-1/ GM-Tg-mg-SE0627-Ag-2 Mouse IL-36RN/IL36RN protein Mouse
GM-Tg-cynog-SE0627-Ag-1/ GM-Tg-cynog-SE0627-Ag-2 Cynomolgus/Rhesus macaque IL-36RN/IL36RN protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0627-Ag-1/ GM-Tg-felg-SE0627-Ag-2 Feline IL-36RN/IL36RN protein Feline
GM-Tg-cang-SE0627-Ag-1/ GM-Tg-cang-SE0627-Ag-2 Canine IL-36RN/IL36RN protein Canine
GM-Tg-bovg-SE0627-Ag-1/ GM-Tg-bovg-SE0627-Ag-2 Bovine IL-36RN/IL36RN protein Bovine
GM-Tg-equg-SE0627-Ag-1/ GM-Tg-equg-SE0627-Ag-2 Equine IL-36RN/IL36RN protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0627-Ag-1/ GM-Tg-hg-SE0627-Ag-2; GM-Tg-rg-SE0627-Ag-1/ GM-Tg-rg-SE0627-Ag-2;
GM-Tg-mg-SE0627-Ag-1/ GM-Tg-mg-SE0627-Ag-2; GM-Tg-cynog-SE0627-Ag-1/ GM-Tg-cynog-SE0627-Ag-2;
GM-Tg-felg-SE0627-Ag-1/ GM-Tg-felg-SE0627-Ag-2; GM-Tg-cang-SE0627-Ag-1/ GM-Tg-cang-SE0627-Ag-2;
GM-Tg-bovg-SE0627-Ag-1/ GM-Tg-bovg-SE0627-Ag-2; GM-Tg-equg-SE0627-Ag-1/ GM-Tg-equg-SE0627-Ag-2
Products Name IL-36RN/IL36RN protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name IL-36RN/IL36RN
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL-36RN/IL36RN protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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