Recombinant multi-species WNT16 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine WNT16 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It contains two transcript variants diverging at the 5' termini. These two variants are proposed to be the products of separate promoters and not to be splice variants from a single promoter. They are differentially expressed in normal tissues, one of which (variant 2) is expressed at significant levels only in the pancreas, whereas another one (variant 1) is expressed more ubiquitously with highest levels in adult kidney, placenta, brain, heart, and spleen. [provided by RefSeq, Jul 2008]
The Alternative Names of target: E130309I19Rik,Protein Wnt-16,WNT16,Wnt16
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0557-Ag-1/ GM-Tg-hg-SE0557-Ag-2 | Human WNT16 protein | Human |
| GM-Tg-rg-SE0557-Ag-1/ GM-Tg-rg-SE0557-Ag-2 | Rat WNT16 protein | Rat |
| GM-Tg-mg-SE0557-Ag-1/ GM-Tg-mg-SE0557-Ag-2 | Mouse WNT16 protein | Mouse |
| GM-Tg-cynog-SE0557-Ag-1/ GM-Tg-cynog-SE0557-Ag-2 | Cynomolgus/Rhesus macaque WNT16 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0557-Ag-1/ GM-Tg-felg-SE0557-Ag-2 | Feline WNT16 protein | Feline |
| GM-Tg-cang-SE0557-Ag-1/ GM-Tg-cang-SE0557-Ag-2 | Canine WNT16 protein | Canine |
| GM-Tg-bovg-SE0557-Ag-1/ GM-Tg-bovg-SE0557-Ag-2 | Bovine WNT16 protein | Bovine |
| GM-Tg-equg-SE0557-Ag-1/ GM-Tg-equg-SE0557-Ag-2 | Equine WNT16 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-SE0557-Ag-1/ GM-Tg-hg-SE0557-Ag-2;
GM-Tg-rg-SE0557-Ag-1/ GM-Tg-rg-SE0557-Ag-2;
GM-Tg-mg-SE0557-Ag-1/ GM-Tg-mg-SE0557-Ag-2; GM-Tg-cynog-SE0557-Ag-1/ GM-Tg-cynog-SE0557-Ag-2; GM-Tg-felg-SE0557-Ag-1/ GM-Tg-felg-SE0557-Ag-2; GM-Tg-cang-SE0557-Ag-1/ GM-Tg-cang-SE0557-Ag-2; GM-Tg-bovg-SE0557-Ag-1/ GM-Tg-bovg-SE0557-Ag-2; GM-Tg-equg-SE0557-Ag-1/ GM-Tg-equg-SE0557-Ag-2 |
| Products Name | WNT16 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | WNT16 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine WNT16 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.