Recombinant multi-species WNT11 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine WNT11 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 97%, 85%, and 63% amino acid identity with mouse, chicken, and Xenopus Wnt11 protein, respectively. This gene may play roles in the development of skeleton, kidney and lung, and is considered to be a plausible candidate gene for High Bone Mass Syndrome. [provided by RefSeq, Jul 2008]
The Alternative Names of target: HWNT11,Protein Wnt-11,WNT11,Wnt11

Target products collectionGo to WNT11 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0556-Ag-1/ GM-Tg-hg-SE0556-Ag-2 Human WNT11 protein Human
GM-Tg-rg-SE0556-Ag-1/ GM-Tg-rg-SE0556-Ag-2 Rat WNT11 protein Rat
GM-Tg-mg-SE0556-Ag-1/ GM-Tg-mg-SE0556-Ag-2 Mouse WNT11 protein Mouse
GM-Tg-cynog-SE0556-Ag-1/ GM-Tg-cynog-SE0556-Ag-2 Cynomolgus/Rhesus macaque WNT11 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0556-Ag-1/ GM-Tg-felg-SE0556-Ag-2 Feline WNT11 protein Feline
GM-Tg-cang-SE0556-Ag-1/ GM-Tg-cang-SE0556-Ag-2 Canine WNT11 protein Canine
GM-Tg-bovg-SE0556-Ag-1/ GM-Tg-bovg-SE0556-Ag-2 Bovine WNT11 protein Bovine
GM-Tg-equg-SE0556-Ag-1/ GM-Tg-equg-SE0556-Ag-2 Equine WNT11 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0556-Ag-1/ GM-Tg-hg-SE0556-Ag-2; GM-Tg-rg-SE0556-Ag-1/ GM-Tg-rg-SE0556-Ag-2;
GM-Tg-mg-SE0556-Ag-1/ GM-Tg-mg-SE0556-Ag-2; GM-Tg-cynog-SE0556-Ag-1/ GM-Tg-cynog-SE0556-Ag-2;
GM-Tg-felg-SE0556-Ag-1/ GM-Tg-felg-SE0556-Ag-2; GM-Tg-cang-SE0556-Ag-1/ GM-Tg-cang-SE0556-Ag-2;
GM-Tg-bovg-SE0556-Ag-1/ GM-Tg-bovg-SE0556-Ag-2; GM-Tg-equg-SE0556-Ag-1/ GM-Tg-equg-SE0556-Ag-2
Products Name WNT11 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name WNT11
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine WNT11 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.