Recombinant multi-species WNT10A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine WNT10A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is strongly expressed in the cell lines of promyelocytic leukemia and Burkitt's lymphoma. In addition, it and another family member, the WNT6 gene, are strongly coexpressed in colorectal cancer cell lines. The gene overexpression may play key roles in carcinogenesis through activation of the WNT-beta-catenin-TCF signaling pathway. This gene and the WNT6 gene are clustered in the chromosome 2q35 region. [provided by RefSeq, Jul 2008]
The Alternative Names of target: ECTD16,OODD,Protein Wnt-10a,SSPS,STHAG4,WNT10A,Wnt10a

Target products collectionGo to WNT10A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0555-Ag-1/ GM-Tg-hg-SE0555-Ag-2 Human WNT10A protein Human
GM-Tg-rg-SE0555-Ag-1/ GM-Tg-rg-SE0555-Ag-2 Rat WNT10A protein Rat
GM-Tg-mg-SE0555-Ag-1/ GM-Tg-mg-SE0555-Ag-2 Mouse WNT10A protein Mouse
GM-Tg-cynog-SE0555-Ag-1/ GM-Tg-cynog-SE0555-Ag-2 Cynomolgus/Rhesus macaque WNT10A protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0555-Ag-1/ GM-Tg-felg-SE0555-Ag-2 Feline WNT10A protein Feline
GM-Tg-cang-SE0555-Ag-1/ GM-Tg-cang-SE0555-Ag-2 Canine WNT10A protein Canine
GM-Tg-bovg-SE0555-Ag-1/ GM-Tg-bovg-SE0555-Ag-2 Bovine WNT10A protein Bovine
GM-Tg-equg-SE0555-Ag-1/ GM-Tg-equg-SE0555-Ag-2 Equine WNT10A protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0555-Ag-1/ GM-Tg-hg-SE0555-Ag-2; GM-Tg-rg-SE0555-Ag-1/ GM-Tg-rg-SE0555-Ag-2;
GM-Tg-mg-SE0555-Ag-1/ GM-Tg-mg-SE0555-Ag-2; GM-Tg-cynog-SE0555-Ag-1/ GM-Tg-cynog-SE0555-Ag-2;
GM-Tg-felg-SE0555-Ag-1/ GM-Tg-felg-SE0555-Ag-2; GM-Tg-cang-SE0555-Ag-1/ GM-Tg-cang-SE0555-Ag-2;
GM-Tg-bovg-SE0555-Ag-1/ GM-Tg-bovg-SE0555-Ag-2; GM-Tg-equg-SE0555-Ag-1/ GM-Tg-equg-SE0555-Ag-2
Products Name WNT10A protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name WNT10A
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine WNT10A protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.