Recombinant multi-species UGT1A10 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine UGT1A10 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has glucuronidase activity on mycophenolic acid, coumarins, and quinolines. [provided by RefSeq, Jul 2008]
The Alternative Names of target: GNT1,UDP-glucuronosyltransferase 1-10 (UDPGT 1-10,UDP-glucuronosyltransferase 1-J (UGT-1J,UDP-glucuronosyltransferase 1A10,UDPGT,UGT-1A,UGT-1J,UGT1,UGT1*10,UGT1-01,UGT1-10,UGT1.1,UGT1.10,UGT1.10),UGT1A,UGT1A1,UGT1A10,UGT1J,UGT1J),hUG-BR1
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0535-Ag-1/ GM-Tg-hg-SE0535-Ag-2 | Human UGT1A10 protein | Human |
| GM-Tg-rg-SE0535-Ag-1/ GM-Tg-rg-SE0535-Ag-2 | Rat UGT1A10 protein | Rat |
| GM-Tg-mg-SE0535-Ag-1/ GM-Tg-mg-SE0535-Ag-2 | Mouse UGT1A10 protein | Mouse |
| GM-Tg-cynog-SE0535-Ag-1/ GM-Tg-cynog-SE0535-Ag-2 | Cynomolgus/Rhesus macaque UGT1A10 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0535-Ag-1/ GM-Tg-felg-SE0535-Ag-2 | Feline UGT1A10 protein | Feline |
| GM-Tg-cang-SE0535-Ag-1/ GM-Tg-cang-SE0535-Ag-2 | Canine UGT1A10 protein | Canine |
| GM-Tg-bovg-SE0535-Ag-1/ GM-Tg-bovg-SE0535-Ag-2 | Bovine UGT1A10 protein | Bovine |
| GM-Tg-equg-SE0535-Ag-1/ GM-Tg-equg-SE0535-Ag-2 | Equine UGT1A10 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-SE0535-Ag-1/ GM-Tg-hg-SE0535-Ag-2;
GM-Tg-rg-SE0535-Ag-1/ GM-Tg-rg-SE0535-Ag-2;
GM-Tg-mg-SE0535-Ag-1/ GM-Tg-mg-SE0535-Ag-2; GM-Tg-cynog-SE0535-Ag-1/ GM-Tg-cynog-SE0535-Ag-2; GM-Tg-felg-SE0535-Ag-1/ GM-Tg-felg-SE0535-Ag-2; GM-Tg-cang-SE0535-Ag-1/ GM-Tg-cang-SE0535-Ag-2; GM-Tg-bovg-SE0535-Ag-1/ GM-Tg-bovg-SE0535-Ag-2; GM-Tg-equg-SE0535-Ag-1/ GM-Tg-equg-SE0535-Ag-2 |
| Products Name | UGT1A10 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | UGT1A10 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine UGT1A10 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
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entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
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characterized by high binding affinity,
exceptional physicochemical stability, and
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Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.