Recombinant multi-species TMED4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TMED4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Involved in positive regulation of I-kappaB kinase/NF-kappaB signaling. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Predicted to be active in several cellular components, including COPII-coated ER to Golgi transport vesicle; Golgi apparatus; and endoplasmic reticulum-Golgi intermediate compartment. [provided by Alliance of Genome Resources, Apr 2022]
The Alternative Names of target: TMED4,Transmembrane emp24 domain-containing protein 4,Endoplasmic reticulum stress-response protein 25 (ERS25), GMP25iso, Putative NF-kappa-B-activating protein 156, p24 family protein alpha-3 (p24alpha3),HNLF,ERS25,p24a3,GMP25iso,p24alpha3

Target products collectionGo to TMED4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0509-Ab-1/ GM-Tg-hg-SE0509-Ab-2 Human TMED4 protein Human
GM-Tg-rg-SE0509-Ab-1/ GM-Tg-rg-SE0509-Ab-2 Rat TMED4 protein Rat
GM-Tg-mg-SE0509-Ab-1/ GM-Tg-mg-SE0509-Ab-2 Mouse TMED4 protein Mouse
GM-Tg-cynog-SE0509-Ab-1/ GM-Tg-cynog-SE0509-Ab-2 Cynomolgus/Rhesus macaque TMED4 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0509-Ab-1/ GM-Tg-felg-SE0509-Ab-2 Feline TMED4 protein Feline
GM-Tg-cang-SE0509-Ab-1/ GM-Tg-cang-SE0509-Ab-2 Canine TMED4 protein Canine
GM-Tg-bovg-SE0509-Ab-1/ GM-Tg-bovg-SE0509-Ab-2 Bovine TMED4 protein Bovine
GM-Tg-equg-SE0509-Ab-1/ GM-Tg-equg-SE0509-Ab-2 Equine TMED4 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0509-Ab-1/ GM-Tg-hg-SE0509-Ab-2; GM-Tg-rg-SE0509-Ab-1/ GM-Tg-rg-SE0509-Ab-2;
GM-Tg-mg-SE0509-Ab-1/ GM-Tg-mg-SE0509-Ab-2; GM-Tg-cynog-SE0509-Ab-1/ GM-Tg-cynog-SE0509-Ab-2;
GM-Tg-felg-SE0509-Ab-1/ GM-Tg-felg-SE0509-Ab-2; GM-Tg-cang-SE0509-Ab-1/ GM-Tg-cang-SE0509-Ab-2;
GM-Tg-bovg-SE0509-Ab-1/ GM-Tg-bovg-SE0509-Ab-2; GM-Tg-equg-SE0509-Ab-1/ GM-Tg-equg-SE0509-Ab-2
Products Name TMED4 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TMED4
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TMED4 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.