Recombinant multi-species SEMA4G protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SEMA4G protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes, some (if not all) containing plexin proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
The Alternative Names of target: SEMA4G,Semaphorin-4G

Target products collectionGo to SEMA4G products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0462-Ab-1/ GM-Tg-hg-SE0462-Ab-2 Human SEMA4G protein Human
GM-Tg-rg-SE0462-Ab-1/ GM-Tg-rg-SE0462-Ab-2 Rat SEMA4G protein Rat
GM-Tg-mg-SE0462-Ab-1/ GM-Tg-mg-SE0462-Ab-2 Mouse SEMA4G protein Mouse
GM-Tg-cynog-SE0462-Ab-1/ GM-Tg-cynog-SE0462-Ab-2 Cynomolgus/Rhesus macaque SEMA4G monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0462-Ab-1/ GM-Tg-felg-SE0462-Ab-2 Feline SEMA4G protein Feline
GM-Tg-cang-SE0462-Ab-1/ GM-Tg-cang-SE0462-Ab-2 Canine SEMA4G protein Canine
GM-Tg-bovg-SE0462-Ab-1/ GM-Tg-bovg-SE0462-Ab-2 Bovine SEMA4G protein Bovine
GM-Tg-equg-SE0462-Ab-1/ GM-Tg-equg-SE0462-Ab-2 Equine SEMA4G protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0462-Ab-1/ GM-Tg-hg-SE0462-Ab-2; GM-Tg-rg-SE0462-Ab-1/ GM-Tg-rg-SE0462-Ab-2;
GM-Tg-mg-SE0462-Ab-1/ GM-Tg-mg-SE0462-Ab-2; GM-Tg-cynog-SE0462-Ab-1/ GM-Tg-cynog-SE0462-Ab-2;
GM-Tg-felg-SE0462-Ab-1/ GM-Tg-felg-SE0462-Ab-2; GM-Tg-cang-SE0462-Ab-1/ GM-Tg-cang-SE0462-Ab-2;
GM-Tg-bovg-SE0462-Ab-1/ GM-Tg-bovg-SE0462-Ab-2; GM-Tg-equg-SE0462-Ab-1/ GM-Tg-equg-SE0462-Ab-2
Products Name SEMA4G protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name SEMA4G
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SEMA4G protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.