Recombinant multi-species SEMA3A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SEMA3A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease. [provided by RefSeq, Jul 2008]
The Alternative Names of target: COLL1,HH16,Hsema-I,Hsema-III,SEMA1,SEMA3A,SEMAD,SEMAIII,SEMAL,SemD,Sema3a,Semad,Semaphorin III (Sema III),Semaphorin-3A,coll-1

Target products collectionGo to SEMA3A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0458-Ag-1/ GM-Tg-hg-SE0458-Ag-2 Human SEMA3A protein Human
GM-Tg-rg-SE0458-Ag-1/ GM-Tg-rg-SE0458-Ag-2 Rat SEMA3A protein Rat
GM-Tg-mg-SE0458-Ag-1/ GM-Tg-mg-SE0458-Ag-2 Mouse SEMA3A protein Mouse
GM-Tg-cynog-SE0458-Ag-1/ GM-Tg-cynog-SE0458-Ag-2 Cynomolgus/Rhesus macaque SEMA3A protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0458-Ag-1/ GM-Tg-felg-SE0458-Ag-2 Feline SEMA3A protein Feline
GM-Tg-cang-SE0458-Ag-1/ GM-Tg-cang-SE0458-Ag-2 Canine SEMA3A protein Canine
GM-Tg-bovg-SE0458-Ag-1/ GM-Tg-bovg-SE0458-Ag-2 Bovine SEMA3A protein Bovine
GM-Tg-equg-SE0458-Ag-1/ GM-Tg-equg-SE0458-Ag-2 Equine SEMA3A protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0458-Ag-1/ GM-Tg-hg-SE0458-Ag-2; GM-Tg-rg-SE0458-Ag-1/ GM-Tg-rg-SE0458-Ag-2;
GM-Tg-mg-SE0458-Ag-1/ GM-Tg-mg-SE0458-Ag-2; GM-Tg-cynog-SE0458-Ag-1/ GM-Tg-cynog-SE0458-Ag-2;
GM-Tg-felg-SE0458-Ag-1/ GM-Tg-felg-SE0458-Ag-2; GM-Tg-cang-SE0458-Ag-1/ GM-Tg-cang-SE0458-Ag-2;
GM-Tg-bovg-SE0458-Ag-1/ GM-Tg-bovg-SE0458-Ag-2; GM-Tg-equg-SE0458-Ag-1/ GM-Tg-equg-SE0458-Ag-2
Products Name SEMA3A protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name SEMA3A
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SEMA3A protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.