Recombinant multi-species RIC3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RIC3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the resistance to inhibitors of cholinesterase 3-like family which functions as a chaperone of specific 5-hydroxytryptamine type 3 receptor and nicotinic acetylcholine receptor subtypes. The encoded protein influences the folding and assembly of these receptor subunits in the endoplasmic reticulum and expression on the cell surface. This protein contains an N-terminal transmembrane domain, a proline-rich spacer, and a cytosolic C-terminal coiled-coil domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]
The Alternative Names of target: AYST720,E130307J04Rik,PRO1385,Protein RIC-3,RIC-3,RIC3,Resistant to inhibitor of cholinesterase 3,Ric3
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0445-Ag-1/ GM-Tg-hg-SE0445-Ag-2 | Human RIC3 protein | Human |
| GM-Tg-rg-SE0445-Ag-1/ GM-Tg-rg-SE0445-Ag-2 | Rat RIC3 protein | Rat |
| GM-Tg-mg-SE0445-Ag-1/ GM-Tg-mg-SE0445-Ag-2 | Mouse RIC3 protein | Mouse |
| GM-Tg-cynog-SE0445-Ag-1/ GM-Tg-cynog-SE0445-Ag-2 | Cynomolgus/Rhesus macaque RIC3 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0445-Ag-1/ GM-Tg-felg-SE0445-Ag-2 | Feline RIC3 protein | Feline |
| GM-Tg-cang-SE0445-Ag-1/ GM-Tg-cang-SE0445-Ag-2 | Canine RIC3 protein | Canine |
| GM-Tg-bovg-SE0445-Ag-1/ GM-Tg-bovg-SE0445-Ag-2 | Bovine RIC3 protein | Bovine |
| GM-Tg-equg-SE0445-Ag-1/ GM-Tg-equg-SE0445-Ag-2 | Equine RIC3 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-SE0445-Ag-1/ GM-Tg-hg-SE0445-Ag-2;
GM-Tg-rg-SE0445-Ag-1/ GM-Tg-rg-SE0445-Ag-2;
GM-Tg-mg-SE0445-Ag-1/ GM-Tg-mg-SE0445-Ag-2; GM-Tg-cynog-SE0445-Ag-1/ GM-Tg-cynog-SE0445-Ag-2; GM-Tg-felg-SE0445-Ag-1/ GM-Tg-felg-SE0445-Ag-2; GM-Tg-cang-SE0445-Ag-1/ GM-Tg-cang-SE0445-Ag-2; GM-Tg-bovg-SE0445-Ag-1/ GM-Tg-bovg-SE0445-Ag-2; GM-Tg-equg-SE0445-Ag-1/ GM-Tg-equg-SE0445-Ag-2 |
| Products Name | RIC3 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | RIC3 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RIC3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.