Recombinant multi-species PLOD2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PLOD2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 2-oxoglutarate 5-dioxygenase 2,BRKS2,D530025C14Rik,LH2,Lysyl hydroxylase 2 (LH2),PLOD2,Plod-2,Plod2,Procollagen-lysine,TLH

Target products collectionGo to PLOD2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0415-Ag-1/ GM-Tg-hg-SE0415-Ag-2 Human PLOD2 protein Human
GM-Tg-rg-SE0415-Ag-1/ GM-Tg-rg-SE0415-Ag-2 Rat PLOD2 protein Rat
GM-Tg-mg-SE0415-Ag-1/ GM-Tg-mg-SE0415-Ag-2 Mouse PLOD2 protein Mouse
GM-Tg-cynog-SE0415-Ag-1/ GM-Tg-cynog-SE0415-Ag-2 Cynomolgus/Rhesus macaque PLOD2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0415-Ag-1/ GM-Tg-felg-SE0415-Ag-2 Feline PLOD2 protein Feline
GM-Tg-cang-SE0415-Ag-1/ GM-Tg-cang-SE0415-Ag-2 Canine PLOD2 protein Canine
GM-Tg-bovg-SE0415-Ag-1/ GM-Tg-bovg-SE0415-Ag-2 Bovine PLOD2 protein Bovine
GM-Tg-equg-SE0415-Ag-1/ GM-Tg-equg-SE0415-Ag-2 Equine PLOD2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0415-Ag-1/ GM-Tg-hg-SE0415-Ag-2; GM-Tg-rg-SE0415-Ag-1/ GM-Tg-rg-SE0415-Ag-2;
GM-Tg-mg-SE0415-Ag-1/ GM-Tg-mg-SE0415-Ag-2; GM-Tg-cynog-SE0415-Ag-1/ GM-Tg-cynog-SE0415-Ag-2;
GM-Tg-felg-SE0415-Ag-1/ GM-Tg-felg-SE0415-Ag-2; GM-Tg-cang-SE0415-Ag-1/ GM-Tg-cang-SE0415-Ag-2;
GM-Tg-bovg-SE0415-Ag-1/ GM-Tg-bovg-SE0415-Ag-2; GM-Tg-equg-SE0415-Ag-1/ GM-Tg-equg-SE0415-Ag-2
Products Name PLOD2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PLOD2
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PLOD2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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