Recombinant multi-species LYPLA3/PLA2G15 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LYPLA3/PLA2G15 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene hydrolyzes lysophosphatidylcholine to glycerophosphorylcholine and a free fatty acid. This enzyme is present in the plasma and thought to be associated with high-density lipoprotein. A later paper contradicts the function of this gene. It demonstrates that this gene encodes a lysosomal enzyme instead of a lysophospholipase and has both calcium-independent phospholipase A2 and transacylase activities. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 1-O-acylceramide synthase (ACS),1-O-acylceramidesynthase,ACS,GXVPLA2,LCAT-like lysophospholipase (LLPL),LLPL,LPLA2,LYPLA3,Lpla2,Lypla3,Lysophospholipase 3,Lysosomal phospholipase A and acyltransferase,Lysosomal phospholipase A2 (LPLA2),PLA2G15,Phospholipase A2 group XV (PLA2G15),Pla2g15
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0410-Ag-1/ GM-Tg-hg-SE0410-Ag-2 | Human LYPLA3/PLA2G15 protein | Human |
| GM-Tg-rg-SE0410-Ag-1/ GM-Tg-rg-SE0410-Ag-2 | Rat LYPLA3/PLA2G15 protein | Rat |
| GM-Tg-mg-SE0410-Ag-1/ GM-Tg-mg-SE0410-Ag-2 | Mouse LYPLA3/PLA2G15 protein | Mouse |
| GM-Tg-cynog-SE0410-Ag-1/ GM-Tg-cynog-SE0410-Ag-2 | Cynomolgus/Rhesus macaque LYPLA3/PLA2G15 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0410-Ag-1/ GM-Tg-felg-SE0410-Ag-2 | Feline LYPLA3/PLA2G15 protein | Feline |
| GM-Tg-cang-SE0410-Ag-1/ GM-Tg-cang-SE0410-Ag-2 | Canine LYPLA3/PLA2G15 protein | Canine |
| GM-Tg-bovg-SE0410-Ag-1/ GM-Tg-bovg-SE0410-Ag-2 | Bovine LYPLA3/PLA2G15 protein | Bovine |
| GM-Tg-equg-SE0410-Ag-1/ GM-Tg-equg-SE0410-Ag-2 | Equine LYPLA3/PLA2G15 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-SE0410-Ag-1/ GM-Tg-hg-SE0410-Ag-2;
GM-Tg-rg-SE0410-Ag-1/ GM-Tg-rg-SE0410-Ag-2;
GM-Tg-mg-SE0410-Ag-1/ GM-Tg-mg-SE0410-Ag-2; GM-Tg-cynog-SE0410-Ag-1/ GM-Tg-cynog-SE0410-Ag-2; GM-Tg-felg-SE0410-Ag-1/ GM-Tg-felg-SE0410-Ag-2; GM-Tg-cang-SE0410-Ag-1/ GM-Tg-cang-SE0410-Ag-2; GM-Tg-bovg-SE0410-Ag-1/ GM-Tg-bovg-SE0410-Ag-2; GM-Tg-equg-SE0410-Ag-1/ GM-Tg-equg-SE0410-Ag-2 |
| Products Name | LYPLA3/PLA2G15 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | LYPLA3/PLA2G15 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LYPLA3/PLA2G15 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
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Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.