Recombinant multi-species Neuromedin B/neuromedin B/NMB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Neuromedin B/neuromedin B/NMB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the bombesin-like family of neuropeptides, which negatively regulate eating behavior. The encoded protein may regulate colonic smooth muscle contraction through binding to its cognate receptor, the neuromedin B receptor (NMBR). Polymorphisms of this gene may be associated with hunger, weight gain and obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
The Alternative Names of target: 3110023K12Rik,NMB,Neuromedin B,Neuromedin-B,Nmb,RGD1562710,neuromedin B

Target products collectionGo to Neuromedin B/neuromedin B/NMB products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0370-Ag-1/ GM-Tg-hg-SE0370-Ag-2 Human Neuromedin B/neuromedin B/NMB protein Human
GM-Tg-rg-SE0370-Ag-1/ GM-Tg-rg-SE0370-Ag-2 Rat Neuromedin B/neuromedin B/NMB protein Rat
GM-Tg-mg-SE0370-Ag-1/ GM-Tg-mg-SE0370-Ag-2 Mouse Neuromedin B/neuromedin B/NMB protein Mouse
GM-Tg-cynog-SE0370-Ag-1/ GM-Tg-cynog-SE0370-Ag-2 Cynomolgus/Rhesus macaque Neuromedin B/neuromedin B/NMB protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0370-Ag-1/ GM-Tg-felg-SE0370-Ag-2 Feline Neuromedin B/neuromedin B/NMB protein Feline
GM-Tg-cang-SE0370-Ag-1/ GM-Tg-cang-SE0370-Ag-2 Canine Neuromedin B/neuromedin B/NMB protein Canine
GM-Tg-bovg-SE0370-Ag-1/ GM-Tg-bovg-SE0370-Ag-2 Bovine Neuromedin B/neuromedin B/NMB protein Bovine
GM-Tg-equg-SE0370-Ag-1/ GM-Tg-equg-SE0370-Ag-2 Equine Neuromedin B/neuromedin B/NMB protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0370-Ag-1/ GM-Tg-hg-SE0370-Ag-2; GM-Tg-rg-SE0370-Ag-1/ GM-Tg-rg-SE0370-Ag-2;
GM-Tg-mg-SE0370-Ag-1/ GM-Tg-mg-SE0370-Ag-2; GM-Tg-cynog-SE0370-Ag-1/ GM-Tg-cynog-SE0370-Ag-2;
GM-Tg-felg-SE0370-Ag-1/ GM-Tg-felg-SE0370-Ag-2; GM-Tg-cang-SE0370-Ag-1/ GM-Tg-cang-SE0370-Ag-2;
GM-Tg-bovg-SE0370-Ag-1/ GM-Tg-bovg-SE0370-Ag-2; GM-Tg-equg-SE0370-Ag-1/ GM-Tg-equg-SE0370-Ag-2
Products Name Neuromedin B/neuromedin B/NMB protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name Neuromedin B/neuromedin B/NMB
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Neuromedin B/neuromedin B/NMB protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.