Recombinant multi-species LAMA5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LAMA5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes one of the vertebrate laminin alpha chains. Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. The protein encoded by this gene is the alpha-5 subunit of of laminin-10 (laminin-511), laminin-11 (laminin-521) and laminin-15 (laminin-523). [provided by RefSeq, Jun 2013]
The Alternative Names of target: BBDS2,LAMA5,Lama5,Laminin subunit alpha-5,Laminin-10 subunit alpha,Laminin-11 subunit alpha,Laminin-15 subunit alpha,NPHS26,[a]5,laminin-511,mKIAA0533
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0299-Ag-1/ GM-Tg-hg-SE0299-Ag-2 | Human LAMA5 protein | Human |
| GM-Tg-rg-SE0299-Ag-1/ GM-Tg-rg-SE0299-Ag-2 | Rat LAMA5 protein | Rat |
| GM-Tg-mg-SE0299-Ag-1/ GM-Tg-mg-SE0299-Ag-2 | Mouse LAMA5 protein | Mouse |
| GM-Tg-cynog-SE0299-Ag-1/ GM-Tg-cynog-SE0299-Ag-2 | Cynomolgus/Rhesus macaque LAMA5 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0299-Ag-1/ GM-Tg-felg-SE0299-Ag-2 | Feline LAMA5 protein | Feline |
| GM-Tg-cang-SE0299-Ag-1/ GM-Tg-cang-SE0299-Ag-2 | Canine LAMA5 protein | Canine |
| GM-Tg-bovg-SE0299-Ag-1/ GM-Tg-bovg-SE0299-Ag-2 | Bovine LAMA5 protein | Bovine |
| GM-Tg-equg-SE0299-Ag-1/ GM-Tg-equg-SE0299-Ag-2 | Equine LAMA5 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-SE0299-Ag-1/ GM-Tg-hg-SE0299-Ag-2;
GM-Tg-rg-SE0299-Ag-1/ GM-Tg-rg-SE0299-Ag-2;
GM-Tg-mg-SE0299-Ag-1/ GM-Tg-mg-SE0299-Ag-2; GM-Tg-cynog-SE0299-Ag-1/ GM-Tg-cynog-SE0299-Ag-2; GM-Tg-felg-SE0299-Ag-1/ GM-Tg-felg-SE0299-Ag-2; GM-Tg-cang-SE0299-Ag-1/ GM-Tg-cang-SE0299-Ag-2; GM-Tg-bovg-SE0299-Ag-1/ GM-Tg-bovg-SE0299-Ag-2; GM-Tg-equg-SE0299-Ag-1/ GM-Tg-equg-SE0299-Ag-2 |
| Products Name | LAMA5 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | LAMA5 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LAMA5 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.