Recombinant multi-species BLTP2/KIAA0100 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BLTP2/KIAA0100 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene was initially characterized in human as having high expression levels in breast carcinomas and breast cancer cell lines. This gene also has increased expression in prostrate cancer cells relative to normal prostrate tissues. Expression of this gene is negatively regulated by direct binding of the microRNA miR-195 to its 3' UTR. miR-195 has been shown to modulate the invasiveness of prostrate cancer cells and xenograft metastases by downgrading expression of this gene. In mouse, the protein encoded by this gene was identified as an antigen on acute monocytic leukemia cells. In human, alternative splicing results in multiple transcript variants encoding distinct isoforms; some of these isoforms are predicted to contain an RNA pol II promoter FMP27 protein domain and a Golgi-body-localization APT1 domain. [provided by RefSeq, Apr 2017]
The Alternative Names of target: 2610507B11Rik,Antigen MLAA-22,BCOX,BCOX1,BLTP2,Bltp2,Breast cancer-overexpressed gene 1 protein,Bridge-like lipid transfer protein family member 2,CT101,D11Bhm178e,D11Bhm179e,E1,FMP27,Hob,KIAA0100,Protein hobbit homolog,RGD1307929,mKIAA0100
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0294-Ag-1/ GM-Tg-hg-SE0294-Ag-2 | Human BLTP2/KIAA0100 protein | Human |
| GM-Tg-rg-SE0294-Ag-1/ GM-Tg-rg-SE0294-Ag-2 | Rat BLTP2/KIAA0100 protein | Rat |
| GM-Tg-mg-SE0294-Ag-1/ GM-Tg-mg-SE0294-Ag-2 | Mouse BLTP2/KIAA0100 protein | Mouse |
| GM-Tg-cynog-SE0294-Ag-1/ GM-Tg-cynog-SE0294-Ag-2 | Cynomolgus/Rhesus macaque BLTP2/KIAA0100 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0294-Ag-1/ GM-Tg-felg-SE0294-Ag-2 | Feline BLTP2/KIAA0100 protein | Feline |
| GM-Tg-cang-SE0294-Ag-1/ GM-Tg-cang-SE0294-Ag-2 | Canine BLTP2/KIAA0100 protein | Canine |
| GM-Tg-bovg-SE0294-Ag-1/ GM-Tg-bovg-SE0294-Ag-2 | Bovine BLTP2/KIAA0100 protein | Bovine |
| GM-Tg-equg-SE0294-Ag-1/ GM-Tg-equg-SE0294-Ag-2 | Equine BLTP2/KIAA0100 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-SE0294-Ag-1/ GM-Tg-hg-SE0294-Ag-2;
GM-Tg-rg-SE0294-Ag-1/ GM-Tg-rg-SE0294-Ag-2;
GM-Tg-mg-SE0294-Ag-1/ GM-Tg-mg-SE0294-Ag-2; GM-Tg-cynog-SE0294-Ag-1/ GM-Tg-cynog-SE0294-Ag-2; GM-Tg-felg-SE0294-Ag-1/ GM-Tg-felg-SE0294-Ag-2; GM-Tg-cang-SE0294-Ag-1/ GM-Tg-cang-SE0294-Ag-2; GM-Tg-bovg-SE0294-Ag-1/ GM-Tg-bovg-SE0294-Ag-2; GM-Tg-equg-SE0294-Ag-1/ GM-Tg-equg-SE0294-Ag-2 |
| Products Name | BLTP2/KIAA0100 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | BLTP2/KIAA0100 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BLTP2/KIAA0100 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
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entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
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characterized by high binding affinity,
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Through
expression in mammalian cell lines, GMab has
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reference antibody. It holds significance in
myriad domains of biological drug
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innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.