Recombinant multi-species ITIH1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ITIH1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the inter-alpha-trypsin inhibitor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the heavy chain of the inter-alpha-trypsin inhibitor complex, which is secreted by hepatocytes into the blood. The heavy chain also interacts with hyaluronan, and this interaction may play a role in ovulation and fertilization, and has been implicated in multiple inflammatory diseases. This gene is present in a gene cluster on chromosome 3. [provided by RefSeq, Nov 2015]
The Alternative Names of target: H1P,IATIH,IGHEP1,ITI heavy chain H1,ITI-HC1,ITIH,ITIH1,Inter-alpha-inhibitor heavy chain 1,Inter-alpha-trypsin inhibitor complex component III,Inter-alpha-trypsin inhibitor heavy chain H1,Intin1,Itih-1,Itih1,SHAP,Serum-derived hyaluronan-associated protein (SHAP)

Target products collectionGo to ITIH1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0288-Ag-1/ GM-Tg-hg-SE0288-Ag-2 Human ITIH1 protein Human
GM-Tg-rg-SE0288-Ag-1/ GM-Tg-rg-SE0288-Ag-2 Rat ITIH1 protein Rat
GM-Tg-mg-SE0288-Ag-1/ GM-Tg-mg-SE0288-Ag-2 Mouse ITIH1 protein Mouse
GM-Tg-cynog-SE0288-Ag-1/ GM-Tg-cynog-SE0288-Ag-2 Cynomolgus/Rhesus macaque ITIH1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0288-Ag-1/ GM-Tg-felg-SE0288-Ag-2 Feline ITIH1 protein Feline
GM-Tg-cang-SE0288-Ag-1/ GM-Tg-cang-SE0288-Ag-2 Canine ITIH1 protein Canine
GM-Tg-bovg-SE0288-Ag-1/ GM-Tg-bovg-SE0288-Ag-2 Bovine ITIH1 protein Bovine
GM-Tg-equg-SE0288-Ag-1/ GM-Tg-equg-SE0288-Ag-2 Equine ITIH1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0288-Ag-1/ GM-Tg-hg-SE0288-Ag-2; GM-Tg-rg-SE0288-Ag-1/ GM-Tg-rg-SE0288-Ag-2;
GM-Tg-mg-SE0288-Ag-1/ GM-Tg-mg-SE0288-Ag-2; GM-Tg-cynog-SE0288-Ag-1/ GM-Tg-cynog-SE0288-Ag-2;
GM-Tg-felg-SE0288-Ag-1/ GM-Tg-felg-SE0288-Ag-2; GM-Tg-cang-SE0288-Ag-1/ GM-Tg-cang-SE0288-Ag-2;
GM-Tg-bovg-SE0288-Ag-1/ GM-Tg-bovg-SE0288-Ag-2; GM-Tg-equg-SE0288-Ag-1/ GM-Tg-equg-SE0288-Ag-2
Products Name ITIH1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name ITIH1
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ITIH1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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