Recombinant multi-species FKRP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FKRP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a protein which is targeted to the medial Golgi apparatus and is necessary for posttranslational modification of dystroglycan. Mutations in this gene have been associated with congenital muscular dystrophy, cognitive disability, and cerebellar cysts. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Oct 2008]
The Alternative Names of target: FKRP,Ribitol 5-phosphate transferase FKRP,Fukutin-related protein, Ribitol-5-phosphate transferase,FKTR,MDC1C,LGMD2I,LGMDR9,MDDGA5,MDDGB5,MDDGC5

Target products collectionGo to FKRP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0222-Ab-1/ GM-Tg-hg-SE0222-Ab-2 Human FKRP protein Human
GM-Tg-rg-SE0222-Ab-1/ GM-Tg-rg-SE0222-Ab-2 Rat FKRP protein Rat
GM-Tg-mg-SE0222-Ab-1/ GM-Tg-mg-SE0222-Ab-2 Mouse FKRP protein Mouse
GM-Tg-cynog-SE0222-Ab-1/ GM-Tg-cynog-SE0222-Ab-2 Cynomolgus/Rhesus macaque FKRP monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0222-Ab-1/ GM-Tg-felg-SE0222-Ab-2 Feline FKRP protein Feline
GM-Tg-cang-SE0222-Ab-1/ GM-Tg-cang-SE0222-Ab-2 Canine FKRP protein Canine
GM-Tg-bovg-SE0222-Ab-1/ GM-Tg-bovg-SE0222-Ab-2 Bovine FKRP protein Bovine
GM-Tg-equg-SE0222-Ab-1/ GM-Tg-equg-SE0222-Ab-2 Equine FKRP protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0222-Ab-1/ GM-Tg-hg-SE0222-Ab-2; GM-Tg-rg-SE0222-Ab-1/ GM-Tg-rg-SE0222-Ab-2;
GM-Tg-mg-SE0222-Ab-1/ GM-Tg-mg-SE0222-Ab-2; GM-Tg-cynog-SE0222-Ab-1/ GM-Tg-cynog-SE0222-Ab-2;
GM-Tg-felg-SE0222-Ab-1/ GM-Tg-felg-SE0222-Ab-2; GM-Tg-cang-SE0222-Ab-1/ GM-Tg-cang-SE0222-Ab-2;
GM-Tg-bovg-SE0222-Ab-1/ GM-Tg-bovg-SE0222-Ab-2; GM-Tg-equg-SE0222-Ab-1/ GM-Tg-equg-SE0222-Ab-2
Products Name FKRP protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name FKRP
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FKRP protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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