Recombinant multi-species FCRLA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FCRLA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a protein similar to receptors for the Fc fragment of gamma immunoglobulin (IgG). These receptors, referred to as FCGRs, mediate the destruction of IgG-coated antigens and of cells induced by antibodies. This encoded protein is selectively expressed in B cells, and may be involved in their development. This protein may also be involved in the development of lymphomas. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
The Alternative Names of target: FCRL,FCRL1,FCRLA,FCRLM1,FCRLX,FCRLb,FCRLc1,FCRLc2,FCRLd,FCRLe,FCRX,FREB,FREB-like,Fc receptor homolog expressed in B-cells,Fc receptor-like A,Fc receptor-like and mucin-like protein 1,Fc receptor-like protein,Fc receptor-related protein X (FcRX),Fcrla,Fcrlm1,Fcrx,Freb1,RGD1306176,mFREB,mFcrX

Target products collectionGo to FCRLA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0213-Ag-1/ GM-Tg-hg-SE0213-Ag-2 Human FCRLA protein Human
GM-Tg-rg-SE0213-Ag-1/ GM-Tg-rg-SE0213-Ag-2 Rat FCRLA protein Rat
GM-Tg-mg-SE0213-Ag-1/ GM-Tg-mg-SE0213-Ag-2 Mouse FCRLA protein Mouse
GM-Tg-cynog-SE0213-Ag-1/ GM-Tg-cynog-SE0213-Ag-2 Cynomolgus/Rhesus macaque FCRLA protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0213-Ag-1/ GM-Tg-felg-SE0213-Ag-2 Feline FCRLA protein Feline
GM-Tg-cang-SE0213-Ag-1/ GM-Tg-cang-SE0213-Ag-2 Canine FCRLA protein Canine
GM-Tg-bovg-SE0213-Ag-1/ GM-Tg-bovg-SE0213-Ag-2 Bovine FCRLA protein Bovine
GM-Tg-equg-SE0213-Ag-1/ GM-Tg-equg-SE0213-Ag-2 Equine FCRLA protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0213-Ag-1/ GM-Tg-hg-SE0213-Ag-2; GM-Tg-rg-SE0213-Ag-1/ GM-Tg-rg-SE0213-Ag-2;
GM-Tg-mg-SE0213-Ag-1/ GM-Tg-mg-SE0213-Ag-2; GM-Tg-cynog-SE0213-Ag-1/ GM-Tg-cynog-SE0213-Ag-2;
GM-Tg-felg-SE0213-Ag-1/ GM-Tg-felg-SE0213-Ag-2; GM-Tg-cang-SE0213-Ag-1/ GM-Tg-cang-SE0213-Ag-2;
GM-Tg-bovg-SE0213-Ag-1/ GM-Tg-bovg-SE0213-Ag-2; GM-Tg-equg-SE0213-Ag-1/ GM-Tg-equg-SE0213-Ag-2
Products Name FCRLA protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name FCRLA
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FCRLA protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.