Recombinant multi-species Collagen Type I/COL1A1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Collagen Type I/COL1A1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]
The Alternative Names of target: Alpha-1 type I collagen,CAFYD,COL1A1,COLIA1,Col1a-1,Col1a1,Cola-1,Cola1,Collagen Type I,Collagen alpha-1(I) chain,EDSARTH1,EDSC,Mov-13,Mov13,OI1,OI2,OI3,OI4

Target products collectionGo to Collagen Type I/COL1A1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0103-Ag-1/ GM-Tg-hg-SE0103-Ag-2 Human Collagen Type I/COL1A1 protein Human
GM-Tg-rg-SE0103-Ag-1/ GM-Tg-rg-SE0103-Ag-2 Rat Collagen Type I/COL1A1 protein Rat
GM-Tg-mg-SE0103-Ag-1/ GM-Tg-mg-SE0103-Ag-2 Mouse Collagen Type I/COL1A1 protein Mouse
GM-Tg-cynog-SE0103-Ag-1/ GM-Tg-cynog-SE0103-Ag-2 Cynomolgus/Rhesus macaque Collagen Type I/COL1A1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0103-Ag-1/ GM-Tg-felg-SE0103-Ag-2 Feline Collagen Type I/COL1A1 protein Feline
GM-Tg-cang-SE0103-Ag-1/ GM-Tg-cang-SE0103-Ag-2 Canine Collagen Type I/COL1A1 protein Canine
GM-Tg-bovg-SE0103-Ag-1/ GM-Tg-bovg-SE0103-Ag-2 Bovine Collagen Type I/COL1A1 protein Bovine
GM-Tg-equg-SE0103-Ag-1/ GM-Tg-equg-SE0103-Ag-2 Equine Collagen Type I/COL1A1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0103-Ag-1/ GM-Tg-hg-SE0103-Ag-2; GM-Tg-rg-SE0103-Ag-1/ GM-Tg-rg-SE0103-Ag-2;
GM-Tg-mg-SE0103-Ag-1/ GM-Tg-mg-SE0103-Ag-2; GM-Tg-cynog-SE0103-Ag-1/ GM-Tg-cynog-SE0103-Ag-2;
GM-Tg-felg-SE0103-Ag-1/ GM-Tg-felg-SE0103-Ag-2; GM-Tg-cang-SE0103-Ag-1/ GM-Tg-cang-SE0103-Ag-2;
GM-Tg-bovg-SE0103-Ag-1/ GM-Tg-bovg-SE0103-Ag-2; GM-Tg-equg-SE0103-Ag-1/ GM-Tg-equg-SE0103-Ag-2
Products Name Collagen Type I/COL1A1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name Collagen Type I/COL1A1
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Collagen Type I/COL1A1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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