Recombinant multi-species Brevican/BCAN protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Brevican/BCAN protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the lectican family of chondroitin sulfate proteoglycans that is specifically expressed in the central nervous system. This protein is developmentally regulated and may function in the formation of the brain extracellular matrix. This protein is highly expressed in gliomas and may promote the growth and cell motility of brain tumor cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]
The Alternative Names of target: ALPBRE,BCAN,BEHAB,Bcan,Brain-enriched hyaluronan-binding protein (BEHAB),Brevican,Brevican core protein,CSPG7,Chondroitin sulfate proteoglycan 7,Cspg7
Go
to Brevican/BCAN products collection
>>
(antibodies,
antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-SE0044-Ag-1/ GM-Tg-hg-SE0044-Ag-2 | Human Brevican/BCAN protein | Human |
GM-Tg-rg-SE0044-Ag-1/ GM-Tg-rg-SE0044-Ag-2 | Rat Brevican/BCAN protein | Rat |
GM-Tg-mg-SE0044-Ag-1/ GM-Tg-mg-SE0044-Ag-2 | Mouse Brevican/BCAN protein | Mouse |
GM-Tg-cynog-SE0044-Ag-1/ GM-Tg-cynog-SE0044-Ag-2 | Cynomolgus/Rhesus macaque Brevican/BCAN protein | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-SE0044-Ag-1/ GM-Tg-felg-SE0044-Ag-2 | Feline Brevican/BCAN protein | Feline |
GM-Tg-cang-SE0044-Ag-1/ GM-Tg-cang-SE0044-Ag-2 | Canine Brevican/BCAN protein | Canine |
GM-Tg-bovg-SE0044-Ag-1/ GM-Tg-bovg-SE0044-Ag-2 | Bovine Brevican/BCAN protein | Bovine |
GM-Tg-equg-SE0044-Ag-1/ GM-Tg-equg-SE0044-Ag-2 | Equine Brevican/BCAN protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. |
GM-Tg-hg-SE0044-Ag-1/ GM-Tg-hg-SE0044-Ag-2;
GM-Tg-rg-SE0044-Ag-1/ GM-Tg-rg-SE0044-Ag-2;
GM-Tg-mg-SE0044-Ag-1/ GM-Tg-mg-SE0044-Ag-2; GM-Tg-cynog-SE0044-Ag-1/ GM-Tg-cynog-SE0044-Ag-2; GM-Tg-felg-SE0044-Ag-1/ GM-Tg-felg-SE0044-Ag-2; GM-Tg-cang-SE0044-Ag-1/ GM-Tg-cang-SE0044-Ag-2; GM-Tg-bovg-SE0044-Ag-1/ GM-Tg-bovg-SE0044-Ag-2; GM-Tg-equg-SE0044-Ag-1/ GM-Tg-equg-SE0044-Ag-2 |
Products Name | Brevican/BCAN protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | Brevican/BCAN |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Brevican/BCAN protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab
GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.