Recombinant multi-species APOL1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine APOL1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]
The Alternative Names of target: APO-L,APOL,APOL-I,APOL1,ApoL),Apolipoprotein L (Apo-L,Apolipoprotein L-I (ApoL-I),Apolipoprotein L1,FSGS4

Target products collectionGo to APOL1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0024-Ag-1/ GM-Tg-hg-SE0024-Ag-2 Human APOL1 protein Human
GM-Tg-rg-SE0024-Ag-1/ GM-Tg-rg-SE0024-Ag-2 Rat APOL1 protein Rat
GM-Tg-mg-SE0024-Ag-1/ GM-Tg-mg-SE0024-Ag-2 Mouse APOL1 protein Mouse
GM-Tg-cynog-SE0024-Ag-1/ GM-Tg-cynog-SE0024-Ag-2 Cynomolgus/Rhesus macaque APOL1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0024-Ag-1/ GM-Tg-felg-SE0024-Ag-2 Feline APOL1 protein Feline
GM-Tg-cang-SE0024-Ag-1/ GM-Tg-cang-SE0024-Ag-2 Canine APOL1 protein Canine
GM-Tg-bovg-SE0024-Ag-1/ GM-Tg-bovg-SE0024-Ag-2 Bovine APOL1 protein Bovine
GM-Tg-equg-SE0024-Ag-1/ GM-Tg-equg-SE0024-Ag-2 Equine APOL1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0024-Ag-1/ GM-Tg-hg-SE0024-Ag-2; GM-Tg-rg-SE0024-Ag-1/ GM-Tg-rg-SE0024-Ag-2;
GM-Tg-mg-SE0024-Ag-1/ GM-Tg-mg-SE0024-Ag-2; GM-Tg-cynog-SE0024-Ag-1/ GM-Tg-cynog-SE0024-Ag-2;
GM-Tg-felg-SE0024-Ag-1/ GM-Tg-felg-SE0024-Ag-2; GM-Tg-cang-SE0024-Ag-1/ GM-Tg-cang-SE0024-Ag-2;
GM-Tg-bovg-SE0024-Ag-1/ GM-Tg-bovg-SE0024-Ag-2; GM-Tg-equg-SE0024-Ag-1/ GM-Tg-equg-SE0024-Ag-2
Products Name APOL1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name APOL1
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine APOL1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.