Recombinant multi-species PPP1R3D protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PPP1R3D protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Phosphorylation of serine and threonine residues in proteins is a crucial step in the regulation of many cellular functions ranging from hormonal regulation to cell division and even short-term memory. The level of phosphorylation is controlled by the opposing actions of protein kinases and protein phosphatases. Protein phosphatase 1 (PP1) is 1 of 4 major serine/threonine-specific protein phosphatases which have been identified in eukaryotic cells. PP1 associates with various regulatory subunits that dictate its subcellular localization and modulate its substrate specificity. Several subunits that target PP1 to glycogen have been identified. This gene encodes a glycogen-targeting subunit of PP1. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 2610024M03Rik,Gm359,PPP1R3D,PPP1R6,Ppp1r3d,Protein phosphatase 1 regulatory subunit 3D,Protein phosphatase 1 regulatory subunit 6 (PP1 subunit R6),Protein phosphatase 1-binding subunit R6
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP9974-Ag-1/ GM-Tg-hg-IP9974-Ag-2 | Human PPP1R3D protein | Human |
| GM-Tg-rg-IP9974-Ag-1/ GM-Tg-rg-IP9974-Ag-2 | Rat PPP1R3D protein | Rat |
| GM-Tg-mg-IP9974-Ag-1/ GM-Tg-mg-IP9974-Ag-2 | Mouse PPP1R3D protein | Mouse |
| GM-Tg-cynog-IP9974-Ag-1/ GM-Tg-cynog-IP9974-Ag-2 | Cynomolgus/Rhesus macaque PPP1R3D protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP9974-Ag-1/ GM-Tg-felg-IP9974-Ag-2 | Feline PPP1R3D protein | Feline |
| GM-Tg-cang-IP9974-Ag-1/ GM-Tg-cang-IP9974-Ag-2 | Canine PPP1R3D protein | Canine |
| GM-Tg-bovg-IP9974-Ag-1/ GM-Tg-bovg-IP9974-Ag-2 | Bovine PPP1R3D protein | Bovine |
| GM-Tg-equg-IP9974-Ag-1/ GM-Tg-equg-IP9974-Ag-2 | Equine PPP1R3D protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP9974-Ag-1/ GM-Tg-hg-IP9974-Ag-2;
GM-Tg-rg-IP9974-Ag-1/ GM-Tg-rg-IP9974-Ag-2;
GM-Tg-mg-IP9974-Ag-1/ GM-Tg-mg-IP9974-Ag-2; GM-Tg-cynog-IP9974-Ag-1/ GM-Tg-cynog-IP9974-Ag-2; GM-Tg-felg-IP9974-Ag-1/ GM-Tg-felg-IP9974-Ag-2; GM-Tg-cang-IP9974-Ag-1/ GM-Tg-cang-IP9974-Ag-2; GM-Tg-bovg-IP9974-Ag-1/ GM-Tg-bovg-IP9974-Ag-2; GM-Tg-equg-IP9974-Ag-1/ GM-Tg-equg-IP9974-Ag-2 |
| Products Name | PPP1R3D protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | PPP1R3D |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PPP1R3D protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.