Recombinant multi-species PPP1R3C protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PPP1R3C protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a carbohydrate binding protein that is a subunit of the protein phosphatase 1 (PP1) complex. PP1 catalyzes reversible protein phosphorylation, which is important in a wide range of cellular activities. The encoded protein affects glycogen biosynthesis by activating glycogen synthase and limiting glycogen breakdown by reducing glycogen phosphorylase activity. DNA hypermethylation of this gene has been found in colorectal cancer patients. The encoded protein also interacts with the laforin protein, which is a protein tyrosine phosphatase implicated in Lafora disease. [provided by RefSeq, Sep 2016]
The Alternative Names of target: PPP1R3C,PPP1R5,PTG,Ppp1r3c,Ppp1r5,Protein phosphatase 1 regulatory subunit 3C,Protein phosphatase 1 regulatory subunit 5 (PP1 subunit R5),Protein targeting to glycogen (PTG),R5
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP9962-Ag-1/ GM-Tg-hg-IP9962-Ag-2 | Human PPP1R3C protein | Human |
| GM-Tg-rg-IP9962-Ag-1/ GM-Tg-rg-IP9962-Ag-2 | Rat PPP1R3C protein | Rat |
| GM-Tg-mg-IP9962-Ag-1/ GM-Tg-mg-IP9962-Ag-2 | Mouse PPP1R3C protein | Mouse |
| GM-Tg-cynog-IP9962-Ag-1/ GM-Tg-cynog-IP9962-Ag-2 | Cynomolgus/Rhesus macaque PPP1R3C protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP9962-Ag-1/ GM-Tg-felg-IP9962-Ag-2 | Feline PPP1R3C protein | Feline |
| GM-Tg-cang-IP9962-Ag-1/ GM-Tg-cang-IP9962-Ag-2 | Canine PPP1R3C protein | Canine |
| GM-Tg-bovg-IP9962-Ag-1/ GM-Tg-bovg-IP9962-Ag-2 | Bovine PPP1R3C protein | Bovine |
| GM-Tg-equg-IP9962-Ag-1/ GM-Tg-equg-IP9962-Ag-2 | Equine PPP1R3C protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP9962-Ag-1/ GM-Tg-hg-IP9962-Ag-2;
GM-Tg-rg-IP9962-Ag-1/ GM-Tg-rg-IP9962-Ag-2;
GM-Tg-mg-IP9962-Ag-1/ GM-Tg-mg-IP9962-Ag-2; GM-Tg-cynog-IP9962-Ag-1/ GM-Tg-cynog-IP9962-Ag-2; GM-Tg-felg-IP9962-Ag-1/ GM-Tg-felg-IP9962-Ag-2; GM-Tg-cang-IP9962-Ag-1/ GM-Tg-cang-IP9962-Ag-2; GM-Tg-bovg-IP9962-Ag-1/ GM-Tg-bovg-IP9962-Ag-2; GM-Tg-equg-IP9962-Ag-1/ GM-Tg-equg-IP9962-Ag-2 |
| Products Name | PPP1R3C protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | PPP1R3C |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PPP1R3C protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
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pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
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