Recombinant multi-species BCOR protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BCOR protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome Y.[provided by RefSeq, Jun 2010]
The Alternative Names of target: 2900008C10Rik,5830466J11Rik,8430401K06Rik,ANOP2,BCL-6 corepressor,BCOR,BCoR,Bcor,BcorR,D930024N20Rik,MAA2,MCOPS2,RGD1562735,mKIAA1575

Target products collectionGo to BCOR products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP9859-Ag-1/ GM-Tg-hg-IP9859-Ag-2 Human BCOR protein Human
GM-Tg-rg-IP9859-Ag-1/ GM-Tg-rg-IP9859-Ag-2 Rat BCOR protein Rat
GM-Tg-mg-IP9859-Ag-1/ GM-Tg-mg-IP9859-Ag-2 Mouse BCOR protein Mouse
GM-Tg-cynog-IP9859-Ag-1/ GM-Tg-cynog-IP9859-Ag-2 Cynomolgus/Rhesus macaque BCOR protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP9859-Ag-1/ GM-Tg-felg-IP9859-Ag-2 Feline BCOR protein Feline
GM-Tg-cang-IP9859-Ag-1/ GM-Tg-cang-IP9859-Ag-2 Canine BCOR protein Canine
GM-Tg-bovg-IP9859-Ag-1/ GM-Tg-bovg-IP9859-Ag-2 Bovine BCOR protein Bovine
GM-Tg-equg-IP9859-Ag-1/ GM-Tg-equg-IP9859-Ag-2 Equine BCOR protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP9859-Ag-1/ GM-Tg-hg-IP9859-Ag-2; GM-Tg-rg-IP9859-Ag-1/ GM-Tg-rg-IP9859-Ag-2;
GM-Tg-mg-IP9859-Ag-1/ GM-Tg-mg-IP9859-Ag-2; GM-Tg-cynog-IP9859-Ag-1/ GM-Tg-cynog-IP9859-Ag-2;
GM-Tg-felg-IP9859-Ag-1/ GM-Tg-felg-IP9859-Ag-2; GM-Tg-cang-IP9859-Ag-1/ GM-Tg-cang-IP9859-Ag-2;
GM-Tg-bovg-IP9859-Ag-1/ GM-Tg-bovg-IP9859-Ag-2; GM-Tg-equg-IP9859-Ag-1/ GM-Tg-equg-IP9859-Ag-2
Products Name BCOR protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name BCOR
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BCOR protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.