Recombinant multi-species HAO1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HAO1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 2-Hydroxyacid oxidase 1,GO,GOX,GOX),GOX1,Glycolate oxidase (GO,Glyoxylate oxidase,Gox1,HAO1,HAOX1,Hao-1,Hao1,XDH1
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP9692-Ag-1/ GM-Tg-hg-IP9692-Ag-2 | Human HAO1 protein | Human |
| GM-Tg-rg-IP9692-Ag-1/ GM-Tg-rg-IP9692-Ag-2 | Rat HAO1 protein | Rat |
| GM-Tg-mg-IP9692-Ag-1/ GM-Tg-mg-IP9692-Ag-2 | Mouse HAO1 protein | Mouse |
| GM-Tg-cynog-IP9692-Ag-1/ GM-Tg-cynog-IP9692-Ag-2 | Cynomolgus/Rhesus macaque HAO1 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP9692-Ag-1/ GM-Tg-felg-IP9692-Ag-2 | Feline HAO1 protein | Feline |
| GM-Tg-cang-IP9692-Ag-1/ GM-Tg-cang-IP9692-Ag-2 | Canine HAO1 protein | Canine |
| GM-Tg-bovg-IP9692-Ag-1/ GM-Tg-bovg-IP9692-Ag-2 | Bovine HAO1 protein | Bovine |
| GM-Tg-equg-IP9692-Ag-1/ GM-Tg-equg-IP9692-Ag-2 | Equine HAO1 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP9692-Ag-1/ GM-Tg-hg-IP9692-Ag-2;
GM-Tg-rg-IP9692-Ag-1/ GM-Tg-rg-IP9692-Ag-2;
GM-Tg-mg-IP9692-Ag-1/ GM-Tg-mg-IP9692-Ag-2; GM-Tg-cynog-IP9692-Ag-1/ GM-Tg-cynog-IP9692-Ag-2; GM-Tg-felg-IP9692-Ag-1/ GM-Tg-felg-IP9692-Ag-2; GM-Tg-cang-IP9692-Ag-1/ GM-Tg-cang-IP9692-Ag-2; GM-Tg-bovg-IP9692-Ag-1/ GM-Tg-bovg-IP9692-Ag-2; GM-Tg-equg-IP9692-Ag-1/ GM-Tg-equg-IP9692-Ag-2 |
| Products Name | HAO1 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | HAO1 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HAO1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.