Recombinant multi-species HAO1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HAO1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 2-Hydroxyacid oxidase 1,GO,GOX,GOX),GOX1,Glycolate oxidase (GO,Glyoxylate oxidase,Gox1,HAO1,HAOX1,Hao-1,Hao1,XDH1

Target products collectionGo to HAO1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP9692-Ag-1/ GM-Tg-hg-IP9692-Ag-2 Human HAO1 protein Human
GM-Tg-rg-IP9692-Ag-1/ GM-Tg-rg-IP9692-Ag-2 Rat HAO1 protein Rat
GM-Tg-mg-IP9692-Ag-1/ GM-Tg-mg-IP9692-Ag-2 Mouse HAO1 protein Mouse
GM-Tg-cynog-IP9692-Ag-1/ GM-Tg-cynog-IP9692-Ag-2 Cynomolgus/Rhesus macaque HAO1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP9692-Ag-1/ GM-Tg-felg-IP9692-Ag-2 Feline HAO1 protein Feline
GM-Tg-cang-IP9692-Ag-1/ GM-Tg-cang-IP9692-Ag-2 Canine HAO1 protein Canine
GM-Tg-bovg-IP9692-Ag-1/ GM-Tg-bovg-IP9692-Ag-2 Bovine HAO1 protein Bovine
GM-Tg-equg-IP9692-Ag-1/ GM-Tg-equg-IP9692-Ag-2 Equine HAO1 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP9692-Ag-1/ GM-Tg-hg-IP9692-Ag-2; GM-Tg-rg-IP9692-Ag-1/ GM-Tg-rg-IP9692-Ag-2;
GM-Tg-mg-IP9692-Ag-1/ GM-Tg-mg-IP9692-Ag-2; GM-Tg-cynog-IP9692-Ag-1/ GM-Tg-cynog-IP9692-Ag-2;
GM-Tg-felg-IP9692-Ag-1/ GM-Tg-felg-IP9692-Ag-2; GM-Tg-cang-IP9692-Ag-1/ GM-Tg-cang-IP9692-Ag-2;
GM-Tg-bovg-IP9692-Ag-1/ GM-Tg-bovg-IP9692-Ag-2; GM-Tg-equg-IP9692-Ag-1/ GM-Tg-equg-IP9692-Ag-2
Products Name HAO1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name HAO1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HAO1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.