Recombinant multi-species POLR2D protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine POLR2D protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes the fourth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. In yeast, this polymerase subunit is associated with the polymerase under suboptimal growth conditions and may have a stress protective role. A sequence for a ribosomal pseudogene is contained within the 3' untranslated region of the transcript from this gene. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 2310002G05Rik,2610028L19Rik,DNA-directed RNA polymerase II subunit D,DNA-directed RNA polymerase II subunit RPB4,HSRBP4,HSRPB4,POLR2D,Polr2d,RBP4,RNA polymerase II 16 kDa subunit (RPB16),RNA polymerase II subunit B4,RPB16,RPB4
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP9688-Ag-1/ GM-Tg-hg-IP9688-Ag-2 | Human POLR2D protein | Human |
| GM-Tg-rg-IP9688-Ag-1/ GM-Tg-rg-IP9688-Ag-2 | Rat POLR2D protein | Rat |
| GM-Tg-mg-IP9688-Ag-1/ GM-Tg-mg-IP9688-Ag-2 | Mouse POLR2D protein | Mouse |
| GM-Tg-cynog-IP9688-Ag-1/ GM-Tg-cynog-IP9688-Ag-2 | Cynomolgus/Rhesus macaque POLR2D protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP9688-Ag-1/ GM-Tg-felg-IP9688-Ag-2 | Feline POLR2D protein | Feline |
| GM-Tg-cang-IP9688-Ag-1/ GM-Tg-cang-IP9688-Ag-2 | Canine POLR2D protein | Canine |
| GM-Tg-bovg-IP9688-Ag-1/ GM-Tg-bovg-IP9688-Ag-2 | Bovine POLR2D protein | Bovine |
| GM-Tg-equg-IP9688-Ag-1/ GM-Tg-equg-IP9688-Ag-2 | Equine POLR2D protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP9688-Ag-1/ GM-Tg-hg-IP9688-Ag-2;
GM-Tg-rg-IP9688-Ag-1/ GM-Tg-rg-IP9688-Ag-2;
GM-Tg-mg-IP9688-Ag-1/ GM-Tg-mg-IP9688-Ag-2; GM-Tg-cynog-IP9688-Ag-1/ GM-Tg-cynog-IP9688-Ag-2; GM-Tg-felg-IP9688-Ag-1/ GM-Tg-felg-IP9688-Ag-2; GM-Tg-cang-IP9688-Ag-1/ GM-Tg-cang-IP9688-Ag-2; GM-Tg-bovg-IP9688-Ag-1/ GM-Tg-bovg-IP9688-Ag-2; GM-Tg-equg-IP9688-Ag-1/ GM-Tg-equg-IP9688-Ag-2 |
| Products Name | POLR2D protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | POLR2D |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine POLR2D protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
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characterized by high binding affinity,
exceptional physicochemical stability, and
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Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
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innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.