Recombinant multi-species ATP6V1B1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ATP6V1B1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain B subunit isoforms and is found in the kidney. Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness. [provided by RefSeq, Jul 2008]
The Alternative Names of target: ATP6B1,ATP6V1B1,Atp6b1,Atp6v1b1,D630003L15,D630030L16Rik,D630039P21Rik,DRTA2,Endomembrane proton pump 58 kDa subunit,RTA1B,V-ATPase subunit B 1,V-type proton ATPase subunit B,VATB,VMA2,VPP3,Vacuolar proton pump subunit B 1,Vpp-3,Vpp3,kidney isoform

Target products collectionGo to ATP6V1B1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP9589-Ag-1/ GM-Tg-hg-IP9589-Ag-2 Human ATP6V1B1 protein Human
GM-Tg-rg-IP9589-Ag-1/ GM-Tg-rg-IP9589-Ag-2 Rat ATP6V1B1 protein Rat
GM-Tg-mg-IP9589-Ag-1/ GM-Tg-mg-IP9589-Ag-2 Mouse ATP6V1B1 protein Mouse
GM-Tg-cynog-IP9589-Ag-1/ GM-Tg-cynog-IP9589-Ag-2 Cynomolgus/Rhesus macaque ATP6V1B1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP9589-Ag-1/ GM-Tg-felg-IP9589-Ag-2 Feline ATP6V1B1 protein Feline
GM-Tg-cang-IP9589-Ag-1/ GM-Tg-cang-IP9589-Ag-2 Canine ATP6V1B1 protein Canine
GM-Tg-bovg-IP9589-Ag-1/ GM-Tg-bovg-IP9589-Ag-2 Bovine ATP6V1B1 protein Bovine
GM-Tg-equg-IP9589-Ag-1/ GM-Tg-equg-IP9589-Ag-2 Equine ATP6V1B1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP9589-Ag-1/ GM-Tg-hg-IP9589-Ag-2; GM-Tg-rg-IP9589-Ag-1/ GM-Tg-rg-IP9589-Ag-2;
GM-Tg-mg-IP9589-Ag-1/ GM-Tg-mg-IP9589-Ag-2; GM-Tg-cynog-IP9589-Ag-1/ GM-Tg-cynog-IP9589-Ag-2;
GM-Tg-felg-IP9589-Ag-1/ GM-Tg-felg-IP9589-Ag-2; GM-Tg-cang-IP9589-Ag-1/ GM-Tg-cang-IP9589-Ag-2;
GM-Tg-bovg-IP9589-Ag-1/ GM-Tg-bovg-IP9589-Ag-2; GM-Tg-equg-IP9589-Ag-1/ GM-Tg-equg-IP9589-Ag-2
Products Name ATP6V1B1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name ATP6V1B1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ATP6V1B1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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