Recombinant multi-species ATP5MC1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ATP5MC1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene is one of three genes that encode subunit c of the proton channel. Each of the three genes have distinct mitochondrial import sequences but encode the identical mature protein. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
The Alternative Names of target: ATP synthase F(0) complex subunit C1,ATP synthase lipid-binding protein,ATP synthase membrane subunit c locus 1,ATP synthase proteolipid P1,ATP synthase proton-transporting mitochondrial F(0) complex subunit C1,ATP5A,ATP5G,ATP5G1,ATP5MC1,ATPase protein 9,ATPase subunit c,Atp5g1,Atp5mc1,mitochondrial
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP9491-Ag-1/ GM-Tg-hg-IP9491-Ag-2 | Human ATP5MC1 protein | Human |
| GM-Tg-rg-IP9491-Ag-1/ GM-Tg-rg-IP9491-Ag-2 | Rat ATP5MC1 protein | Rat |
| GM-Tg-mg-IP9491-Ag-1/ GM-Tg-mg-IP9491-Ag-2 | Mouse ATP5MC1 protein | Mouse |
| GM-Tg-cynog-IP9491-Ag-1/ GM-Tg-cynog-IP9491-Ag-2 | Cynomolgus/Rhesus macaque ATP5MC1 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP9491-Ag-1/ GM-Tg-felg-IP9491-Ag-2 | Feline ATP5MC1 protein | Feline |
| GM-Tg-cang-IP9491-Ag-1/ GM-Tg-cang-IP9491-Ag-2 | Canine ATP5MC1 protein | Canine |
| GM-Tg-bovg-IP9491-Ag-1/ GM-Tg-bovg-IP9491-Ag-2 | Bovine ATP5MC1 protein | Bovine |
| GM-Tg-equg-IP9491-Ag-1/ GM-Tg-equg-IP9491-Ag-2 | Equine ATP5MC1 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP9491-Ag-1/ GM-Tg-hg-IP9491-Ag-2;
GM-Tg-rg-IP9491-Ag-1/ GM-Tg-rg-IP9491-Ag-2;
GM-Tg-mg-IP9491-Ag-1/ GM-Tg-mg-IP9491-Ag-2; GM-Tg-cynog-IP9491-Ag-1/ GM-Tg-cynog-IP9491-Ag-2; GM-Tg-felg-IP9491-Ag-1/ GM-Tg-felg-IP9491-Ag-2; GM-Tg-cang-IP9491-Ag-1/ GM-Tg-cang-IP9491-Ag-2; GM-Tg-bovg-IP9491-Ag-1/ GM-Tg-bovg-IP9491-Ag-2; GM-Tg-equg-IP9491-Ag-1/ GM-Tg-equg-IP9491-Ag-2 |
| Products Name | ATP5MC1 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | ATP5MC1 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ATP5MC1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
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(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.