Recombinant multi-species PDE6G/H/PDE6H protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PDE6G/H/PDE6H protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes the inhibitory (or gamma) subunit of the cone-specific cGMP phosphodiesterase, which is a tetramer composed of two catalytic chains (alpha and beta), and two inhibitory chains (gamma). It is specifically expressed in the retina, and is involved in the transmission and amplification of the visual signal. Mutations in this gene are associated with retinal cone dystrophy type 3A (RCD3A). [provided by RefSeq, Mar 2010]
The Alternative Names of target: 5'-cyclic phosphodiesterase subunit gamma,A930033D18Rik,ACHM6,GMP-PDE gamma,H,PDE6G,PDE6H,PDEgamma,Pde6g,Pde6h,RCD3,Retinal cone rhodopsin-sensitive cGMP 3'

Target products collectionGo to PDE6G/H/PDE6H products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP9444-Ag-1/ GM-Tg-hg-IP9444-Ag-2 Human PDE6G/H/PDE6H protein Human
GM-Tg-rg-IP9444-Ag-1/ GM-Tg-rg-IP9444-Ag-2 Rat PDE6G/H/PDE6H protein Rat
GM-Tg-mg-IP9444-Ag-1/ GM-Tg-mg-IP9444-Ag-2 Mouse PDE6G/H/PDE6H protein Mouse
GM-Tg-cynog-IP9444-Ag-1/ GM-Tg-cynog-IP9444-Ag-2 Cynomolgus/Rhesus macaque PDE6G/H/PDE6H protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP9444-Ag-1/ GM-Tg-felg-IP9444-Ag-2 Feline PDE6G/H/PDE6H protein Feline
GM-Tg-cang-IP9444-Ag-1/ GM-Tg-cang-IP9444-Ag-2 Canine PDE6G/H/PDE6H protein Canine
GM-Tg-bovg-IP9444-Ag-1/ GM-Tg-bovg-IP9444-Ag-2 Bovine PDE6G/H/PDE6H protein Bovine
GM-Tg-equg-IP9444-Ag-1/ GM-Tg-equg-IP9444-Ag-2 Equine PDE6G/H/PDE6H protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP9444-Ag-1/ GM-Tg-hg-IP9444-Ag-2; GM-Tg-rg-IP9444-Ag-1/ GM-Tg-rg-IP9444-Ag-2;
GM-Tg-mg-IP9444-Ag-1/ GM-Tg-mg-IP9444-Ag-2; GM-Tg-cynog-IP9444-Ag-1/ GM-Tg-cynog-IP9444-Ag-2;
GM-Tg-felg-IP9444-Ag-1/ GM-Tg-felg-IP9444-Ag-2; GM-Tg-cang-IP9444-Ag-1/ GM-Tg-cang-IP9444-Ag-2;
GM-Tg-bovg-IP9444-Ag-1/ GM-Tg-bovg-IP9444-Ag-2; GM-Tg-equg-IP9444-Ag-1/ GM-Tg-equg-IP9444-Ag-2
Products Name PDE6G/H/PDE6H protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PDE6G/H/PDE6H
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PDE6G/H/PDE6H protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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