Recombinant multi-species YTHDF2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine YTHDF2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the YTH (YT521-B homology) superfamily containing YTH domain. The YTH domain is typical for the eukaryotes and is particularly abundant in plants. The YTH domain is usually located in the middle of the protein sequence and may function in binding to RNA. In addition to a YTH domain, this protein has a proline rich region which may be involved in signal transduction. An Alu-rich domain has been identified in one of the introns of this gene, which is thought to be associated with human longevity. In addition, reciprocal translocations between this gene and the Runx1 (AML1) gene on chromosome 21 has been observed in patients with acute myeloid leukemia. This gene was initially mapped to chromosome 14, which was later turned out to be a pseudogene. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Oct 2012]
The Alternative Names of target: 9430020E02Rik,CAHL,CLL-associated antigen KW-14,DF2,HGRG8,High-glucose-regulated protein 8,NY-REN-2,Renal carcinoma antigen NY-REN-2,YTH domain-containing family protein 2,YTHDF2,Ythdf2
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP9426-Ag-1/ GM-Tg-hg-IP9426-Ag-2 | Human YTHDF2 protein | Human |
| GM-Tg-rg-IP9426-Ag-1/ GM-Tg-rg-IP9426-Ag-2 | Rat YTHDF2 protein | Rat |
| GM-Tg-mg-IP9426-Ag-1/ GM-Tg-mg-IP9426-Ag-2 | Mouse YTHDF2 protein | Mouse |
| GM-Tg-cynog-IP9426-Ag-1/ GM-Tg-cynog-IP9426-Ag-2 | Cynomolgus/Rhesus macaque YTHDF2 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP9426-Ag-1/ GM-Tg-felg-IP9426-Ag-2 | Feline YTHDF2 protein | Feline |
| GM-Tg-cang-IP9426-Ag-1/ GM-Tg-cang-IP9426-Ag-2 | Canine YTHDF2 protein | Canine |
| GM-Tg-bovg-IP9426-Ag-1/ GM-Tg-bovg-IP9426-Ag-2 | Bovine YTHDF2 protein | Bovine |
| GM-Tg-equg-IP9426-Ag-1/ GM-Tg-equg-IP9426-Ag-2 | Equine YTHDF2 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP9426-Ag-1/ GM-Tg-hg-IP9426-Ag-2;
GM-Tg-rg-IP9426-Ag-1/ GM-Tg-rg-IP9426-Ag-2;
GM-Tg-mg-IP9426-Ag-1/ GM-Tg-mg-IP9426-Ag-2; GM-Tg-cynog-IP9426-Ag-1/ GM-Tg-cynog-IP9426-Ag-2; GM-Tg-felg-IP9426-Ag-1/ GM-Tg-felg-IP9426-Ag-2; GM-Tg-cang-IP9426-Ag-1/ GM-Tg-cang-IP9426-Ag-2; GM-Tg-bovg-IP9426-Ag-1/ GM-Tg-bovg-IP9426-Ag-2; GM-Tg-equg-IP9426-Ag-1/ GM-Tg-equg-IP9426-Ag-2 |
| Products Name | YTHDF2 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | YTHDF2 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine YTHDF2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
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characterized by high binding affinity,
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Through
expression in mammalian cell lines, GMab has
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reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.