Recombinant multi-species AMPK Gamma 2/PRKAG2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AMPK Gamma 2/PRKAG2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family. Mutations in this gene have been associated with Wolff-Parkinson-White syndrome, familial hypertrophic cardiomyopathy, and glycogen storage disease of the heart. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jan 2015]
The Alternative Names of target: 2410051C13Rik,5'-AMP-activated protein kinase subunit gamma-2,AAKG,AAKG2,AMPK Gamma 2,AMPK gamma2,AMPK subunit gamma-2,CMH6,H91620p,PRKAG2,Prkag2,WPWS

Target products collectionGo to AMPK Gamma 2/PRKAG2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP9419-Ag-1/ GM-Tg-hg-IP9419-Ag-2 Human AMPK Gamma 2/PRKAG2 protein Human
GM-Tg-rg-IP9419-Ag-1/ GM-Tg-rg-IP9419-Ag-2 Rat AMPK Gamma 2/PRKAG2 protein Rat
GM-Tg-mg-IP9419-Ag-1/ GM-Tg-mg-IP9419-Ag-2 Mouse AMPK Gamma 2/PRKAG2 protein Mouse
GM-Tg-cynog-IP9419-Ag-1/ GM-Tg-cynog-IP9419-Ag-2 Cynomolgus/Rhesus macaque AMPK Gamma 2/PRKAG2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP9419-Ag-1/ GM-Tg-felg-IP9419-Ag-2 Feline AMPK Gamma 2/PRKAG2 protein Feline
GM-Tg-cang-IP9419-Ag-1/ GM-Tg-cang-IP9419-Ag-2 Canine AMPK Gamma 2/PRKAG2 protein Canine
GM-Tg-bovg-IP9419-Ag-1/ GM-Tg-bovg-IP9419-Ag-2 Bovine AMPK Gamma 2/PRKAG2 protein Bovine
GM-Tg-equg-IP9419-Ag-1/ GM-Tg-equg-IP9419-Ag-2 Equine AMPK Gamma 2/PRKAG2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP9419-Ag-1/ GM-Tg-hg-IP9419-Ag-2; GM-Tg-rg-IP9419-Ag-1/ GM-Tg-rg-IP9419-Ag-2;
GM-Tg-mg-IP9419-Ag-1/ GM-Tg-mg-IP9419-Ag-2; GM-Tg-cynog-IP9419-Ag-1/ GM-Tg-cynog-IP9419-Ag-2;
GM-Tg-felg-IP9419-Ag-1/ GM-Tg-felg-IP9419-Ag-2; GM-Tg-cang-IP9419-Ag-1/ GM-Tg-cang-IP9419-Ag-2;
GM-Tg-bovg-IP9419-Ag-1/ GM-Tg-bovg-IP9419-Ag-2; GM-Tg-equg-IP9419-Ag-1/ GM-Tg-equg-IP9419-Ag-2
Products Name AMPK Gamma 2/PRKAG2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name AMPK Gamma 2/PRKAG2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AMPK Gamma 2/PRKAG2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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